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瑞士人群中的红细胞抗原JAL:家族研究表明JAL是一种Rh抗原(RH48)。

The red cell antigen JAL in the Swiss population: family studies showing that JAL is an Rh antigen (RH48).

作者信息

Poole J, Hustinx H, Gerber H, Lomas C, Liew Y W, Tippett P

机构信息

Blood Group Reference Laboratory, Bristol, UK.

出版信息

Vox Sang. 1990;59(1):44-7. doi: 10.1111/j.1423-0410.1990.tb02113.x.

DOI:10.1111/j.1423-0410.1990.tb02113.x
PMID:2118699
Abstract

The JAL antigen was found to have an overall frequency of 0.004% in the Swiss population and 0.06% in French-speaking Swiss. Family studies of 5 JAL+ individuals have shown that the JAL antigen is not part of the ABO, MNSs, Fy, Jk and Co blood group systems, or the Se system, nor is it X- or Y-linked. JAL is encoded by the RH locus or by a very closely linked locus. The number RH48 (4.48) has been assigned for JAL by the International Society of Blood Transfusion Working Party on Terminology for Red Cell Surface Antigens.

摘要

在瑞士人群中,JAL抗原的总体频率为0.004%,在讲法语的瑞士人中为0.06%。对5名JAL阳性个体的家族研究表明,JAL抗原不属于ABO、MNSs、Fy、Jk和Co血型系统,也不属于Se系统,且与X或Y染色体无关。JAL由RH基因座或紧密连锁的基因座编码。国际输血协会红细胞表面抗原术语工作小组已将编号RH48(4.48)指定给JAL。

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引用本文的文献

1
Red cells from the original JAL+ proband are also DAK+ and STEM+.来自最初 JAL+先证者的红细胞也是 DAK+和 STEM+。
Vox Sang. 2011 Jul;101(1):61-4. doi: 10.1111/j.1423-0410.2010.01465.x. Epub 2011 Apr 8.
2
JAL (RH48) blood group antigen: serologic observations.JAL(RH48)血型抗原:血清学观察
Transfusion. 2009 Apr;49(4):719-24. doi: 10.1111/j.1537-2995.2008.02025.x. Epub 2008 Dec 15.
3
The JAL antigen (RH48) is the result of a change in RHCE that encodes Arg114Trp.JAL抗原(RH48)是由编码精氨酸114色氨酸的RHCE发生变化所致。
Transfusion. 2009 Apr;49(4):725-32. doi: 10.1111/j.1537-2995.2008.02034.x. Epub 2008 Dec 23.