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2%氯己定与5.25%次氯酸钠冲洗液对术后疼痛影响的比较:一项随机临床试验

Comparison of 2% chlorhexidine and 5.25% sodium hypochlorite irrigating solutions on postoperative pain: a randomized clinical trial.

作者信息

Bashetty Kusum, Hegde Jayshree

机构信息

Department of Conservative Dentistry & Endodontics, The Oxford Dental College & Hospital, Bangalore, Karnataka, India.

出版信息

Indian J Dent Res. 2010 Oct-Dec;21(4):523-7. doi: 10.4103/0970-9290.74225.

Abstract

AIM

To compare the levels of postoperative pain after cleaning and shaping of root canals using two different root canal irrigants for debridement.

MATERIALS AND METHODS

Forty patients with irreversible pulpitis, pulp necrosis and non-vital teeth exhibiting acute apical periodontitis requiring root canal treatment were included. At random, canals were cleaned and shaped with the following protocols. 2% chlorhexidine solution in group I and 5.25% sodium hypochlorite solution in group II were used as an irrigants. Access cavities were closed with a sterile cotton pellet and cavit. The patients recorded degree of pain at various time intervals after cleaning and shaping on a visual analogue scale for 1 week.

RESULTS

The mean pain score for group I was between 0.65 and 3.35 and for group II was between 0.95 and 4.50. There was significant difference in the pain level between the two groups only at 6 th hour postoperatively (P<0.05) and the pain was more in sodium hypochlorite group.

CONCLUSIONS

More pain was present in teeth irrigated using 5.25% sodium hypochlorite when compared to that in teeth irrigated using 2% chlorhexidine solution. Significant difference in pain level was present only at 6th hour postoperatively, and at all other periods (24 th hour, 4 th and 7 th days) there was no significant difference in pain level between the two groups.

摘要

目的

比较使用两种不同根管冲洗剂进行清创后根管清理和成形术后的疼痛程度。

材料与方法

纳入40例患有不可复性牙髓炎、牙髓坏死及无活力牙且伴有急性根尖周炎需要进行根管治疗的患者。随机采用以下方案对根管进行清理和成形。第一组使用2%氯己定溶液,第二组使用5.25%次氯酸钠溶液作为冲洗剂。用无菌棉球和暂封剂封闭开髓洞。患者在清理和成形后的1周内,每隔一段时间用视觉模拟评分法记录疼痛程度。

结果

第一组的平均疼痛评分为0.65至3.35,第二组为0.95至4.50。两组之间仅在术后第6小时疼痛程度有显著差异(P<0.05),且次氯酸钠组疼痛更明显。

结论

与使用2%氯己定溶液冲洗的牙齿相比,使用5.25%次氯酸钠冲洗的牙齿疼痛更明显。疼痛程度的显著差异仅出现在术后第6小时,在其他所有时间段(第24小时、第4天和第7天)两组之间疼痛程度无显著差异。

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