Ercan Ertuğrul, Ozekinci Tuncer, Atakul Fatma, Gül Kadri
Dental Faculty, Department of Operative Dentistry, University of Dicle, Diyarbakir City, Turkey.
J Endod. 2004 Feb;30(2):84-7. doi: 10.1097/00004770-200402000-00005.
In this study, the antibacterial activity of the different antibacterial solutions using as root canal irrigant was compared in the teeth with pulpal necrosis and with periapical pathosis. Thirty root canals of incisors and premolars of 20 patients were used. Before and after the root canal preparation, two canal samples were obtained by a harvesting method using a sterile paper point in the first appointment. During the biomechanical preparation, both irrigant solutions were used for each tooth which were randomly divided into two groups. Last samples were also obtained before the root filling procedure. Samples obtained from the root canals were subjected to microbiologic processing, including anaerobic incubation on trypticase soy agar for 5 to 7 days. After counting of CFU on the plates, we concluded that both chlorhexidine gluconate and sodium hypochlorite were significantly effective to reduce the microorganisms in the teeth with necrotic pulp, periapical pathologies, or both, and could be used successfully as an irrigant solution.
在本研究中，比较了用作根管冲洗剂的不同抗菌溶液对患有牙髓坏死和根尖周病变牙齿的抗菌活性。使用了20名患者的30颗切牙和前磨牙的根管。在根管预备前后，在首次就诊时通过无菌纸尖采集法获取两份根管样本。在生物力学预备过程中，每种溶液均用于随机分为两组的每颗牙齿。在根管充填术前也获取了最后的样本。从根管获得的样本进行微生物学处理，包括在胰蛋白酶大豆琼脂上厌氧培养5至7天。在平板上计数CFU后，我们得出结论，葡萄糖酸氯己定和次氯酸钠对减少患有牙髓坏死、根尖周病变或两者皆有的牙齿中的微生物均有显著效果，并且可以成功用作冲洗液。
