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[根治性肾切除术后25年发生肾细胞癌胰腺转移]

[Pancreatic metastasis from renal cell carcinoma 25 years after radical nephrectomy].

作者信息

Yokonishi Tetsuhiro, Ito Yusuke, Osaka Kimito, Komiya Atsushi, Kobayashi Kazuki, Sakai Naoki, Noguchi Sumio, Kishi Hiroichi, Satomi Yoshiaki, Mogaki Masatoshi, Tsuura Yukio, Mizuno Nobuhiko, Ikeda Ichirou

机构信息

The Department of Urology, Yokosuka Kyosai Hospital, Japan.

出版信息

Hinyokika Kiyo. 2010 Nov;56(11):629-33.

Abstract

We report a case of pancreatic metastasis from renal cell carcinoma detected 25 years after radical nephrectomy. A 74-year-old man, who had undergone radical nephrectomy for renal cell carcinoma at age 49, was found by computed tomography to have a strongly enhanced mass on the pancreatic head. The patient underwent pancreaticoduodenectomy and the pathological diagnosis was metastatic renal cell carcinoma. This was evidently a slow growing tumor because the metastatic pancreas tumor was well demarcated and the metastasis was found 25 years after the primary operation. Aggressive surgical treatment of isolated metastatic lesions offers a chance of long-term survival. Patients with a history of RCC should undergo a long-term follow-up to detect and evaluate metastasis to pancreas as well as other organs.

摘要

我们报告一例肾细胞癌胰腺转移病例,该病例在根治性肾切除术后25年才被发现。一名74岁男性,49岁时因肾细胞癌接受了根治性肾切除术,计算机断层扫描发现其胰头部有一个强化明显的肿块。患者接受了胰十二指肠切除术,病理诊断为转移性肾细胞癌。这显然是一个生长缓慢的肿瘤,因为转移性胰腺肿瘤边界清晰,且转移是在初次手术后25年才被发现。对孤立性转移病灶进行积极的手术治疗可提供长期生存的机会。有肾细胞癌病史的患者应接受长期随访,以检测和评估胰腺及其他器官的转移情况。

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