Babu Abraham Samuel, Noone Manjula Sukumari, Haneef Mohammed, Naryanan Shijoy M
Department of Rehabilitation, CSI Mission Hosptial, Codacal, Kerala, India.
Heart Views. 2010 Jun;11(2):52-6. doi: 10.4103/1995-705X.73209.
Phase-1 Cardiac Rehabilitation (CR) is an important part in the treatment of patients with ST-Elevation Myocardial Infarction (STEMI). Lack of literature in the rural Indian setting led to the design of this study.
Secondary care rural hospital, non-randomized experimental study.
Fifteen historical controls and 15 prospectively enrolled patients between January 2007 and December 2007. The prospectively enrolled patients received the phase-1, exercise-based, protocol-guided CR. At discharge, the six-minute walk test (6MWT) distance, Borg's Rating of Perceived Exertion (RPE) after the 6MWT, time to return to baseline parameters after the 6MWT, and complications were assessed.
Independent t-test and the Mann Whitney test.
Statistically significant (P < 0.01) differences in ratings of perceived exertion (RPE) and time to return to baseline parameters post the 6MWT were seen in the experimental group ((2 vs. 4 and 5.47 vs. 7.93 minutes, respectively). No significant changes in the 6MWT distance between the groups were noticed (470±151.76 m and 379±170.70 m, respectively). No adverse events during the 6MWT and the phase-1 CR were observed.
Protocol-guided, phase-1 CR produces a much faster return of heart rate and blood pressure to baseline following the 6MWT, without producing a great rise in the RPE during the 6MWT, which suggests a training benefit among these patients. The 6MWT can be safely administered in this rural population. However, larger studies will be required to validate these results.
一期心脏康复(CR)是ST段抬高型心肌梗死(STEMI)患者治疗的重要组成部分。印度农村地区缺乏相关文献,因此开展了本研究。
农村二级护理医院,非随机实验研究。
选取2007年1月至2007年12月期间的15例历史对照患者和15例前瞻性入组患者。前瞻性入组患者接受基于运动的一期方案指导心脏康复。出院时,评估6分钟步行试验(6MWT)距离、6MWT后的Borg自觉用力评分(RPE)、6MWT后恢复至基线参数的时间以及并发症。
独立t检验和曼-惠特尼检验。
实验组在自觉用力评分(RPE)以及6MWT后恢复至基线参数的时间方面存在统计学显著差异(P<0.01)(分别为2分钟对4分钟和5.47分钟对7.93分钟)。两组间6MWT距离无显著变化(分别为470±151.76米和379±170.70米)。6MWT和一期CR期间未观察到不良事件。
方案指导的一期CR使心率和血压在6MWT后更快恢复至基线,且6MWT期间RPE没有大幅上升,这表明这些患者能从训练中获益。6MWT可在该农村人群中安全实施。然而,需要更大规模的研究来验证这些结果。