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本文引用的文献

1
Altered circadian rhythm of pulp sensibility in elderly diabetic and hypertensive patients.老年糖尿病和高血压患者牙髓敏感性昼夜节律的改变
Chin Med J (Engl). 2007 Jun 5;120(11):1024-6.
2
Diabetic neuropathies.糖尿病性神经病变
Pract Neurol. 2007 Apr;7(2):82-92.
3
Diabetic cardiovascular autonomic neuropathy.糖尿病性心血管自主神经病变
Circulation. 2007 Jan 23;115(3):387-97. doi: 10.1161/CIRCULATIONAHA.106.634949.
4
Value of sympathetic skin response test in the early diagnosis of diabetic neuropathy.交感神经皮肤反应试验在糖尿病性神经病变早期诊断中的价值
Chin Med J (Engl). 2004 Sep;117(9):1317-20.
5
Influence of autonomic nervous system dysfunction on the development of type 2 diabetes: the CARDIA study.自主神经系统功能障碍对2型糖尿病发生发展的影响：CARDIA研究
Diabetes Care. 2003 Nov;26(11):3035-41. doi: 10.2337/diacare.26.11.3035.
6
Circadian variation in the onset of myocardial infarction: effect of duration of diabetes.
Diabetes. 2003 Jun;52(6):1464-8. doi: 10.2337/diabetes.52.6.1464.
7
Diabetic autonomic neuropathy.糖尿病性自主神经病变
Diabetes Care. 2003 May;26(5):1553-79. doi: 10.2337/diacare.26.5.1553.
8
Pulse pressure and diurnal blood pressure variation: association with micro- and macrovascular complications in type 2 diabetes.脉压与血压昼夜变化：与2型糖尿病微血管和大血管并发症的关联
Am J Hypertens. 2002 Mar;15(3):244-50. doi: 10.1016/s0895-7061(01)02281-6.
9
Factors determining the 24-h blood pressure profile in normotensive patients with type 1 and type 2 diabetes.1型和2型糖尿病正常血压患者24小时血压谱的决定因素
J Hum Hypertens. 2001 Apr;15(4):239-46. doi: 10.1038/sj.jhh.1001170.
10
Increased QTc dispersion is related to blunted circadian blood pressure variation in normoalbuminuric type 1 diabetic patients.QTc离散度增加与正常白蛋白尿的1型糖尿病患者昼夜血压变化减弱有关。
Diabetes. 2001 Apr;50(4):837-42. doi: 10.2337/diabetes.50.4.837.

糖尿病患者急性ST段抬高型心肌梗死发病的昼夜节律变化。

Circadian variation on the onset of acute ST segment elevation myocardial infarction in diabetic subjects.

作者信息

Li Jing, Hua Qi, Pi Lin, Tan Jing, Li Boyu

机构信息

Heart Center; Beijing Xuanwu Hospital Affiliated Capital Medical University, Beijing, PRC.

出版信息

J Cardiovasc Dis Res. 2010 Jan;1(1):23-6. doi: 10.4103/0975-3583.59981.

DOI:10.4103/0975-3583.59981
PMID:21188086
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3004166/
Abstract

BACKGROUND#ENTITYSTARTX02014;: Previous studies have shown that there is a circadian variation in the incidence of acute myocardial infarction. The aim of this study is to examine the circadian rhythms of acute myocardial infarction in patients with type 2 diabetes. METHODS AND RESULTS#ENTITYSTARTX02014;: 1016 consecutive patients admitted to a coronary care unit with acute ST elevation myocardial infarction were studied from January 2004 to December 2008. All patients were divided into two groups according to with or without diabetes. Admission rates were calculated according to the 6-hour interval of the day (circadian rhythm). The data were analyzed for variations within subgroups. In diabetic group, number of patients in the first to fourth quarters was 38, 45, 43, 46 respectively (NS). The corresponding figures for the controls were 174, 295, 183, 192 (P<0.01). The difference between the two groups was significant (P<0.02). CONCLUSION#ENTITYSTARTX02014;: There is no a significant circadian variation in the onset of acute myocardial infarction in diabetic subjects.

摘要

背景

既往研究表明，急性心肌梗死的发病率存在昼夜变化。本研究旨在探讨2型糖尿病患者急性心肌梗死的昼夜节律。

方法与结果

对2004年1月至2008年12月期间连续收治于冠心病监护病房的1016例急性ST段抬高型心肌梗死患者进行研究。所有患者根据有无糖尿病分为两组。根据一天中的6小时间隔（昼夜节律）计算入院率。对亚组内的差异进行数据分析。糖尿病组第一至四季度的患者人数分别为38、45、43、46例（无显著性差异）。对照组的相应数字分别为174、295、183、192例（P<0.01）。两组间差异有显著性（P<0.02）。

结论

糖尿病患者急性心肌梗死发病不存在显著的昼夜变化。