糖尿病患者急性ST段抬高型心肌梗死发病的昼夜节律变化。
Circadian variation on the onset of acute ST segment elevation myocardial infarction in diabetic subjects.
作者信息
Li Jing, Hua Qi, Pi Lin, Tan Jing, Li Boyu
机构信息
Heart Center; Beijing Xuanwu Hospital Affiliated Capital Medical University, Beijing, PRC.
出版信息
J Cardiovasc Dis Res. 2010 Jan;1(1):23-6. doi: 10.4103/0975-3583.59981.
BACKGROUND#ENTITYSTARTX02014;: Previous studies have shown that there is a circadian variation in the incidence of acute myocardial infarction. The aim of this study is to examine the circadian rhythms of acute myocardial infarction in patients with type 2 diabetes. METHODS AND RESULTS#ENTITYSTARTX02014;: 1016 consecutive patients admitted to a coronary care unit with acute ST elevation myocardial infarction were studied from January 2004 to December 2008. All patients were divided into two groups according to with or without diabetes. Admission rates were calculated according to the 6-hour interval of the day (circadian rhythm). The data were analyzed for variations within subgroups. In diabetic group, number of patients in the first to fourth quarters was 38, 45, 43, 46 respectively (NS). The corresponding figures for the controls were 174, 295, 183, 192 (P<0.01). The difference between the two groups was significant (P<0.02). CONCLUSION#ENTITYSTARTX02014;: There is no a significant circadian variation in the onset of acute myocardial infarction in diabetic subjects.
背景
既往研究表明，急性心肌梗死的发病率存在昼夜变化。本研究旨在探讨2型糖尿病患者急性心肌梗死的昼夜节律。
方法与结果
对2004年1月至2008年12月期间连续收治于冠心病监护病房的1016例急性ST段抬高型心肌梗死患者进行研究。所有患者根据有无糖尿病分为两组。根据一天中的6小时间隔（昼夜节律）计算入院率。对亚组内的差异进行数据分析。糖尿病组第一至四季度的患者人数分别为38、45、43、46例（无显著性差异）。对照组的相应数字分别为174、295、183、192例（P<0.01）。两组间差异有显著性（P<0.02）。
结论
糖尿病患者急性心肌梗死发病不存在显著的昼夜变化。
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