Department of Medical Microbiology, UMCG, University of Groningen, P.O. Box 30001, 9700 RB Groningen, Netherlands.
Antimicrob Agents Chemother. 2011 Mar;55(3):1199-203. doi: 10.1128/AAC.01771-09. Epub 2010 Dec 28.
The susceptibility of 14 species of 115 Gram-positive anaerobic cocci (GPAC) was determined for 14 antibiotics. To assure correct identification, strains were genotypically identified by fluorescence in situ hybridization and sequencing. Susceptibility differences (MIC₅₀ and MIC₉₀) for penicillin G, clindamycin, tigecycline, levofloxacin, amoxicillin-clavulanic acid, cefoxitin, ertapenem, meropenem, metronidazole, and doxycycline were found for the three clinically most relevant GPAC species: Finegoldia magna, Parvimonas micra, and Peptoniphilus harei.
测定了 115 株 14 种革兰阳性厌氧球菌（GPAC）对 14 种抗生素的敏感性。为了确保正确鉴定，通过荧光原位杂交和测序对菌株进行了基因分型鉴定。对于临床上最相关的三种 GPAC 种属（巨球形金杆菌、小微单胞菌和海雷葡萄球菌），发现了青霉素 G、克林霉素、替加环素、左氧氟沙星、阿莫西林-克拉维酸、头孢西丁、厄他培南、美罗培南、甲硝唑和多西环素的敏感性差异（MIC₅₀和 MIC₉₀）。
