Kölzsch Marita, Bolbrinker Juliane, Huber Matthias, Kreutz Reinhold
Institut für Klinische Pharmakologie und Toxikologie, Charité-Universitätsmedizin Berlin.
Med Monatsschr Pharm. 2010 Aug;33(8):295-302.
Appropriate pharmacotherapy is one of the most important topics due to demographic development in many industrialised countries. The purpose of our work was to evaluate and adjust a French consensus list for Germany.
We conducted a thorough literature review with regard to the safety of drugs for the elderly.
Originally, 34 criteria containing drugs or drug classes were classified as inappropriate. From these, we evaluated 12 criteria as appropriate, and all others as potentially inappropriate, too. Frequently, drugs affecting the central nervous system, for example anticholinergics and benzodiazepines, were evaluated as potentially inappropriate medication.
Our adapted list may be used as recommendation for appropriate drug prescribing in the elderly in Germany.
由于许多工业化国家的人口发展，适当的药物治疗是最重要的话题之一。我们工作的目的是评估并调整一份适用于德国的法国共识清单。
我们针对老年人用药安全性进行了全面的文献综述。
最初，34条包含药物或药物类别的标准被归类为不适当。其中，我们评估了12条标准为适当，而其他所有标准也被评估为可能不适当。影响中枢神经系统的药物，例如抗胆碱能药物和苯二氮䓬类药物，经常被评估为可能不适当的药物。
我们调整后的清单可作为德国老年人适当药物处方的推荐。
