Saraf Kedar, Shashikanth M C, Priy Tulasi, Sultana Nishat, Chaitanya Nallan C S K
Department of Oral Medicine and Radiology, SMBT Dental College and Hospital, Sangamner, Maharashtra.
J Assoc Physicians India. 2010 Aug;58:488-90, 495-6.
Probiotics are dietary supplements containing potentially beneficial bacteria or yeasts. They are administered in different quantities that allow for colon colonization. These products help in stimulating health promoting flora and also suppressing the pathologic colonization and disease spread. The use of probiotic plays an important aspect in dentistry too ever since the oral infections occupied the prime space among the other infections effecting the humans. This concept of microbial ecologic change both for medical and dental changes has accumulated a lot of evidence in recent times. But to date, no substantial literature and use has been postulated. There are claims that probiotics strengthen the immune system to combat allergies, stress, exposure to toxic substances and other diseases. There are reports of their beneficial use in HIV infection and cancers, mostly, the colo-rectal carcinomas. Their use in pre malignant and malignant oral disorders is yet to be probed. Strains of genera lactobacillus and bifidobacterium are the most widely used probiotic bacteria. This review is an attempt to discuss briefly the role of probiotics in medicine and dentistry.
益生菌是含有潜在有益细菌或酵母的膳食补充剂。它们以不同的剂量给药，以实现结肠定植。这些产品有助于刺激促进健康的菌群，同时抑制病理性定植和疾病传播。自从口腔感染在影响人类的其他感染中占据首要位置以来，益生菌在牙科领域也发挥着重要作用。近年来，这种微生物生态变化在医学和牙科方面的概念积累了大量证据。但迄今为止，尚未有大量文献及应用被提出。有人声称益生菌能增强免疫系统以对抗过敏、压力、接触有毒物质和其他疾病。有报道称它们在艾滋病毒感染和癌症（主要是结直肠癌）中具有有益作用。它们在口腔癌前病变和恶性病变中的应用尚待探索。乳酸杆菌属和双歧杆菌属的菌株是最广泛使用的益生菌。这篇综述旨在简要讨论益生菌在医学和牙科中的作用。
