Department of Organic Chemistry, Faculty of Sciences, University of Granada, C. U. Fuentenueva s/n, 18071 Granada, Spain.
J Org Chem. 2011 Jan 21;76(2):732-5. doi: 10.1021/jo102269d. Epub 2010 Dec 29.
A mild, highly regio- and stereoselective method for the crotylation of aldehydes and ketones mediated/catalyzed by titanocene(III) is described. Optimized conditions permit the selective generation of γ-adducts in high yields together with high stereoselectivity, with a predominance of anti stereoisomers.
描述了由钛（III）介导/催化的醛和酮的高区域和立体选择性的温和克罗蒂化方法。优化条件允许以高产率和高立体选择性选择性地生成γ-加合物，反式异构体占优势。
