Sandrin C, Peypoux F, Michel G
Laboratoire de Biochimie Microbienne, Université Claude Bernard, Lyon I, France.
Biotechnol Appl Biochem. 1990 Aug;12(4):370-5.
Of the 13 strains of Bacillus subtilis tested for the coproduction of the lipopeptide surfactin and the antifungal lipopeptides of the iturin family, only 1 produced both lipopeptides with a high yield. The cultures were made in a synthetic medium. Several L-amino acids and various carbon sources were good substrates for the lipopeptide production. The maximum yield of surfactin was about 110 mg/liter and that of iturin A about 39 mg/liter/absorbance unit for the best strain, B. subtilis S 499.
在对13株枯草芽孢杆菌进行检测以确定其是否能共同产生脂肽表面活性素和伊枯草菌素家族的抗真菌脂肽时，只有1株能高产这两种脂肽。培养是在合成培养基中进行的。几种L-氨基酸和各种碳源是脂肽生产的良好底物。对于最佳菌株枯草芽孢杆菌S 499，表面活性素的最高产量约为110毫克/升，伊枯草菌素A的产量约为39毫克/升/吸光度单位。
