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枯草芽孢杆菌生物活性脂肽伊枯草菌素A和表面活性素的相互作用

Interactions of bioactive lipopeptides, iturin A and surfactin from Bacillus subtilis.

作者信息

Thimon L, Peypoux F, Maget-Dana R, Roux B, Michel G

机构信息

Laboratoire de Biochimie Microbienne, Université Lyon 1, Villeurbanne, France.

出版信息

Biotechnol Appl Biochem. 1992 Oct;16(2):144-51.

PMID:1457050
Abstract

The antifungal activity of iturin A and its interaction with erythrocyte membranes were enhanced in the presence of surfactin. The modification of the properties of iturin A was explained by the formation of mixed iturin A-surfactin micelles. Such mixed micelles were easily generated when both lipopeptides were in aqueous solutions in the absence of mineral salts but the formation of these micelles did not occur when the solutions contained a high molarity of mineral cations.

摘要

在表面活性素存在的情况下,伊枯草菌素A的抗真菌活性及其与红细胞膜的相互作用增强。伊枯草菌素A性质的改变是由伊枯草菌素A-表面活性素混合胶束的形成所解释的。当两种脂肽在无矿物盐的水溶液中时,这种混合胶束很容易形成,但当溶液中含有高摩尔浓度的矿物阳离子时,这些胶束不会形成。

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