Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, USA.
Org Lett. 2011 Feb 4;13(3):434-7. doi: 10.1021/ol102767j. Epub 2010 Dec 30.
This paper describes the regioselective diamination of conjugated dienes using inexpensive Cu(I) as catalyst and N,N-di-tert-butylthiadiaziridine 1,1-dioxide as nitrogen source. The regioselectivity of diamination is likely due to dual mechanistic pathways which are greatly influenced by reaction conditions and the nature of the diene. A variety of useful internal and terminal cyclic sulfamides can be obtained in good yield.
本文描述了使用廉价的 Cu(I) 作为催化剂和 N,N-二特丁基硫代二氮杂环丁烷 1,1-二氧化物作为氮源,对共轭二烯进行区域选择性的二胺化反应。二胺化的区域选择性可能归因于两种机械途径,这些途径受反应条件和二烯的性质影响很大。多种有用的内部和末端环状磺酰胺可以以良好的产率得到。