Gastroenterology and Hepatology Division; University of Torino, San Giovanni Battista Hospital, Torino, Italy.
Dig Liver Dis. 2011 Jan;43 Suppl 1:S15-8. doi: 10.1016/S1590-8658(10)60687-1.
The hepatitis D virus (HDV) was discovered in Italy in the mid-1970s during a major outbreak of hepatitis D in the Mediterranean basin. The outbreak has been brought under control in Europe and throughout the industrialized world in the last twenty years; in parallel, the clinical pattern of HDV disease has consistently changed. Though the decline of hepatitis D has diminished attention to this problem and at present testing for HDV is not seldom neglected, hepatitis D is not eradicated in Europe and its circulation did not decline further in the last decade. Fresh new cases are cumulating in migrants from HDV endemic areas of the developing world. Hepatitis D remains a major health problem in many developing areas with outbreaks of the disease continuing to be reported from Asia, Africa and South Africa.
丁型肝炎病毒（HDV）于 20 世纪 70 年代中期在意大利被发现，当时地中海盆地爆发了一场大规模的丁型肝炎疫情。在过去的二十年里，该疫情在欧洲和整个工业化世界得到了控制；与此同时，HDV 疾病的临床模式也在不断变化。尽管丁型肝炎的减少降低了人们对这个问题的关注，而且目前对 HDV 的检测常常被忽视，但在欧洲，丁型肝炎并没有被根除，其传播在过去十年也没有进一步下降。来自发展中国家丁型肝炎流行地区的移民中不断出现新的病例。在许多发展中地区，丁型肝炎仍然是一个主要的健康问题，亚洲、非洲和南非仍不断有该病爆发的报告。
