UCD School of Biomolecular and Biomedical Science, UCD Conway Institute and UCD Institute for Sport and Health, UCD Dublin, Belield, Dublin 4, Ireland.
Front Biosci (Landmark Ed). 2011 Jan 1;16(1):315-39. doi: 10.2741/3690.
Aberrant alterations in glucose and lipid concentrations and their pathways of metabolism are a hallmark of diabetes. However, much less is known about alterations in concentrations of amino acids and their pathways of metabolism in diabetes. In this review we have attempted to highlight, integrate and discuss common alterations in amino acid metabolism in a wide variety of cells and tissues and relate these changes to alterations in endocrine, physiologic and immune function in diabetes.
葡萄糖和脂质浓度及其代谢途径的异常改变是糖尿病的一个标志。然而，关于糖尿病中氨基酸浓度及其代谢途径的改变，人们知之甚少。在这篇综述中，我们试图强调、整合和讨论各种细胞和组织中氨基酸代谢的常见改变，并将这些变化与糖尿病中内分泌、生理和免疫功能的改变联系起来。
