Department of Internal Medicine, Coney Island Hospital, Brooklyn, NY, USA.
J Multidiscip Healthc. 2008 Oct 1;1:93-6. doi: 10.2147/jmdh.s3018.
This is a case of a 70-year-old man with severe peripheral neuropathy, type 2 diabetes and progressively worsening cerebellar ataxia. He was found to have circulating antigliadin and antireticulin antibodies compatible with celiac disease in the absence of intestinal pathology. The peripheral neuropathy improved with a gluten-free diet, antioxidants and intravenous immunoglobulin, whereas the ataxia did not. This case illustrates the need to test for celiac disease in patients with idiopathic ataxia and peripheral neuropathy and the need for alternative therapies for ataxia.
这是一例 70 岁男性，患有严重周围神经病、2 型糖尿病和进行性小脑共济失调。在没有肠道病理学的情况下，他被发现有循环抗麦胶蛋白和抗内因子抗体，与乳糜泻相符。周围神经病在采用无麸质饮食、抗氧化剂和静脉注射免疫球蛋白后得到改善，而共济失调则没有。该病例说明有必要在特发性共济失调和周围神经病患者中检测乳糜泻，并且需要针对共济失调采用替代疗法。
