Gastroenterology Department, POVISA Hospital, C/Salamanca 5, Vigo, Pontevedra, Spain.
Rev Esp Enferm Dig. 2010 Dec;102(12):704-10. doi: 10.4321/s1130-01082010001200005.
Self-expandable plastic stents (SEPS) are increasingly being used for treatment of postoperative esophageal leak. This complication occurs in 4-27% of patients after radical gastrectomy, and has a high mortality rate up to 60%.The aim of this study is to evaluate the efficacy of SEPS (Polyflex®) for treatment of post-operative esophago-jejuno anastomosis leak after radical gastrectomy for gastric cancer.
During one year period patients who underwent a radical gastrectomy in our hospital for gastric cancer and developed a postoperative anastomotic leak were prospectively included in the study after signing a consent form, and treated with SEPS placement under endoscopic and fluoroscopic control for leak occlusion.
Four patients were included (3 men/1 woman). The mean interval between operation and SEPS placement was 16 days (range: 4-34). SEPS deployment was easily performed in all patients with complete occlusion of esophageal lumen in three patients. In the fourth patient we needed to deploy a second coaxial stent to achieve a complete occlusion of the fistula. SEPS migration did not happen in our series. One patient had already developed a mediastinitis by the time we placed the SEPS and he died 3 days later. Extraction of the SEPS was easily performed 4-8 weeks after deployment.
We achieved a complete healing of the anastomotic fistula after radical gastrectomy in 3 out of 4 patients, without major complications related to SEPS. Placement of SEPS is an appealing minimally invasive alternative to surgical repair for patients with postoperative anastomotic leak.
自膨式塑料支架(SEPS)越来越多地用于治疗术后食管漏。这种并发症在根治性胃切除术后的患者中发生率为 4-27%,死亡率高达 60%。本研究旨在评估 SEPS(Polyflex®)治疗胃癌根治性胃切除术后食管-空肠吻合口漏的疗效。
在一年的时间里,在我院接受根治性胃切除术治疗胃癌并发生术后吻合口漏的患者,在签署知情同意书后,前瞻性地纳入本研究,并在内镜和透视控制下放置 SEPS 以闭塞漏口。
共纳入 4 例患者(3 例男性/1 例女性)。SEPS 放置与手术的平均间隔时间为 16 天(范围:4-34 天)。所有患者均能顺利放置 SEPS,3 例患者完全闭塞食管腔,第 4 例患者需要再放置一个同轴支架以完全闭塞瘘口。在本系列中,SEPS 未发生迁移。在我们放置 SEPS 时,有 1 例患者已经发生纵隔炎,他在 3 天后死亡。SEPS 放置 4-8 周后,很容易取出。
我们在 4 例患者中的 3 例中实现了根治性胃切除术后吻合口瘘的完全愈合,没有与 SEPS 相关的重大并发症。对于术后吻合口漏的患者,SEPS 放置是一种有吸引力的微创替代手术修复的方法。