Department of Medicine and University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.
Nutr Rev. 2011 Jan;69(1):52-60. doi: 10.1111/j.1753-4887.2010.00361.x.
Understanding why we eat and the motivational factors driving food choices is important for addressing the epidemics of obesity, diabetes, and cardiovascular disease. Eating behavior is a complex interplay of physiological, psychological, social, and genetic factors that influence meal timing, quantity of food intake, and food preference. Reviewed here is the current and emerging knowledge of the genetic influences on eating behavior and how these relate to obesity; particular emphasis is placed on the genetics of taste, meal size, and selection, and the emerging use of functional magnetic resonance imaging to study neural reactions in response to food stimuli in normal, overweight, and obese individuals.
了解我们为什么进食以及驱动食物选择的动机因素对于解决肥胖、糖尿病和心血管疾病的流行至关重要。进食行为是生理、心理、社会和遗传因素的复杂相互作用,这些因素影响进餐时间、食物摄入量和食物偏好。本文综述了目前关于遗传因素对进食行为的影响以及这些因素与肥胖的关系的最新知识;特别强调了味觉、进餐量和选择的遗传学,以及新兴的功能性磁共振成像在研究正常、超重和肥胖个体对食物刺激的神经反应中的应用。