de Roo Marthe, Hartman Catharina A, Wagtendonk Alfred, Hoek Hans W, Lakerveld Jeroen, Kretschmer Tina
Faculty of Behavioral and Social Sciences, Department of Pedagogy and Educational Sciences, University of Groningen, Groningen, the Netherlands.
Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Obesity (Silver Spring). 2025 Feb;33(2):385-394. doi: 10.1002/oby.24213. Epub 2025 Jan 19.
We examined BMI development across changes in the built environment during the transition from adolescence to young adulthood and explored the moderating role of genetic risk.
We used longitudinal data from individuals aged 16 to 25 years in the TRacking Adolescents' Individual Lives Survey (TRAILS) that we linked to built environment data for 2006, 2010, and 2016 from the Geoscience and Health Cohort Consortium (GECCO). We fitted a latent growth model of BMI and examined associations of changes in fast-food restaurant density and walkability with changes in BMI (n = 2735), as well as interactions of changes in fast-food restaurant density and walkability with genetic risk (n = 1676).
Changes in fast-food restaurant density (e.g., Δ2010-2006: β = -0.04, 95% CI: -0.11 to 0.03) and walkability (e.g., Δ2010-2006: β = -0.05, 95% CI: -0.14 to 0.05) were not associated with BMI changes. Additionally, genetic risk did not moderate these associations.
We found limited evidence that moving to neighborhoods with higher fast-food restaurant density or less walkability was associated with BMI changes or that genetic risk moderated these associations. Our findings suggest that associations between the built environment and BMI changes during the transition into young adulthood are likely small.
我们研究了从青春期到青年期建筑环境变化过程中的体重指数（BMI）发展情况，并探讨了遗传风险的调节作用。
我们使用了来自“追踪青少年个体生活调查”（TRAILS）中16至25岁个体的纵向数据，并将其与地球科学与健康队列联盟（GECCO）2006年、2010年和2016年的建筑环境数据相链接。我们拟合了BMI的潜在增长模型，研究了快餐店密度和步行便利性的变化与BMI变化之间的关联（n = 2735），以及快餐店密度和步行便利性的变化与遗传风险之间的相互作用（n = 1676）。
快餐店密度的变化（例如，2010 - 2006年的变化：β = -0.04，95%置信区间：-0.11至0.03）和步行便利性的变化（例如，2010 - 2006年的变化：β = -0.05，95%置信区间：-0.14至0.05）与BMI变化无关。此外，遗传风险并未调节这些关联。
我们发现有限的证据表明，搬到快餐店密度较高或步行便利性较差的社区与BMI变化有关，或者遗传风险调节了这些关联。我们的研究结果表明，在向青年期过渡期间，建筑环境与BMI变化之间的关联可能很小。
