Colgate Australian Clinical Dental Research Centre, Dental School, University of Adelaide, Adelaide, South Australia, Australia.
Int J Evid Based Healthc. 2010 Sep;8(3):129-39. doi: 10.1111/j.1744-1609.2010.00171.x.
For many years an association between the low bone density of osteoporosis and increased risk of periodontal bone loss has been suspected. In this review the relationship between osteoporosis and periodontal disease is considered.
For this narrative review a very broad search strategy of the literature was developed using both PubMed and Scopus databases using the search words "perio" and "osteoporosis". The reference lists from the selected papers were also scanned and this provided an additional source of papers for inclusion. The inclusion/exclusion criteria, were also quite liberal with only those papers dealing with bisphosphonates and osteonecrosis of the jaws, osteoporosis in edentulous individuals, as well as those not written in English being excluded.
The data available suggest that reduced bone mineral density is a shared risk factor for periodontitis rather than a causal factor. However, more prospective studies are required to fully determine what, if any, relationship truly exists between periodontitis and reduced bone mineral density.
More prospective studies are required to determine what, if any, relationships exist between periodontal disease and reduced bone mineral density.
多年来，人们一直怀疑骨质疏松症的低骨密度与牙周骨丢失风险增加之间存在关联。在本次综述中，我们考虑了骨质疏松症和牙周病之间的关系。
为了进行本次叙述性综述，我们使用 PubMed 和 Scopus 数据库制定了非常广泛的文献检索策略，使用的检索词为“perio”和“osteoporosis”。还扫描了选定论文的参考文献列表，这为纳入更多论文提供了来源。纳入/排除标准也非常宽松，仅排除了那些涉及双膦酸盐和颌骨骨坏死、无牙颌个体骨质疏松症以及非英文撰写的论文。
现有数据表明，骨矿物质密度降低是牙周炎的共同危险因素，而不是致病因素。然而，需要更多的前瞻性研究来充分确定牙周炎和骨矿物质密度降低之间是否存在任何关系。
需要更多的前瞻性研究来确定牙周病和骨矿物质密度降低之间是否存在任何关系。
