University of Stirling, Scotland, UK.
Br J Health Psychol. 2011 Sep;16(3):592-609. doi: 10.1348/2044-8287.002000. Epub 2010 Nov 19.
The aim of this study was to investigate factors that may explain variance in adherence to medication in stroke patients. Design. A qualitative comparison of high and low adherers to medication.
Thirteen participants, selected from a sample of 180 stroke survivors because they self-reported the lowest adherence to medication regimes, were matched with 13 reporting maximal adherence. All took part in semi-structured qualitative interviews.
Thematic analysis revealed that those with poor adherence to medication reported both intentional and non-intentional non-adherence. Two main themes emerged: the importance of stability of a medication routine and beliefs about medication and treatment. High adherers reported remembering to take their medication and seeking support from both family and health professionals. They also had a realistic understanding of the consequences of non-adherence, and believed their medicine did them more good than harm. Low adherers reported forgetting their medication, sometimes intentionally not taking their medication and receiving poor support from medical staff. They disliked taking their medication, had limited knowledge about the medication rationale or intentions, and often disputed its benefits.
Our findings suggest that appropriate medication and illness beliefs coupled with a stable medication routine are helpful in achieving optimal medication adherence in stroke patients. Interventions designed to target both intentional and non-intentional adherence may help maximize medication adherence in stroke patients.
本研究旨在探讨可能解释中风患者药物治疗依从性差异的因素。设计:对药物治疗依从性高和低的患者进行定性比较。
从 180 名中风幸存者中选择了 13 名参与者,他们自我报告的药物治疗依从性最低,与报告最大依从性的 13 名参与者相匹配。所有参与者都参加了半结构化的定性访谈。
主题分析显示,药物治疗依从性差的患者报告了有意和无意的不依从。出现了两个主要主题:药物治疗常规的稳定性以及对药物和治疗的信念的重要性。高依从性患者报告记得服用药物,并从家人和医疗保健专业人员那里寻求支持。他们还对不依从的后果有现实的认识,并相信他们的药物对他们的好处大于坏处。低依从性患者报告忘记服药,有时故意不服药,并且从医务人员那里得到的支持很差。他们不喜欢服用药物,对药物的基本原理或意图知之甚少,并且经常对其益处持怀疑态度。
我们的研究结果表明,适当的药物和疾病信念以及稳定的药物治疗常规有助于提高中风患者的药物治疗依从性。针对有意和无意依从性的干预措施可能有助于最大限度地提高中风患者的药物治疗依从性。