沙特阿拉伯王国中风患者的药物依从性及相关因素
Medications adherence and associated factors among patients with stroke in the Kingdom of Saudi Arabia.
作者信息
Basheti Iman A, Ayasrah Shahnaz M, Ahmad Muayyad M, Abu-Snieneh Hana M, Abuadas Fuad H
机构信息
Faculty of Pharmacy, Applied Science Private University, 11931, Amman, Jordan; Faculty of Pharmacy, The University of Sydney, 2006, Sydney, Australia.
PhD. Associate professor, Department of Applied Science/Nursing, Al-Balqa Applied University, Al-Salt - Jordan.
出版信息
Pharm Pract (Granada). 2022 Oct-Dec;20(4):2736. doi: 10.18549/PharmPract.2022.4.2736. Epub 2022 Oct 12.
BACKGROUND
Stroke is one of the most significant neurological problems around the world, and is considered a leading cause of death. Due to polypharmacy and multimorbidity, stroke patients are susceptible to have lower levels of adherence to their medications and self-care activities.
METHODS
Patients who have suffered a stroke and had recently been admitted to public hospital were approached for recruitment. Patients' adherence to their medications was examined using a validated questionnaire during an interview between the principal investigator and the patients, where patients' adherence to their self-care activities was assessed using a developed, validated and previously published questionnaire as well. Reasons for lack of adherence was explored from the patients. Verification of patient's details and medications was done via the patient's hospital file.
RESULTS
The mean age of the participants (n=173) was 53.21 (SD= 8.61) years. Assessing patients' adherence to medications showed that more than half of them stated that they sometimes/often forgot to take their medication/s, while 41.0% sometimes/often stopped their medication/s from time to time. The mean adherence to medications score (out of 28) was 18.39 (SD=2.1), with 83.8% having a low adherence level. It is found that patients who did not take their medications were due to forgetfulness (46.8%) and complications from taking the medications (20.2%). Better adherence was associated with higher educational level, higher number of medical conditions, and higher frequency of glucose monitoring. Adherence to self-care activities showed that majority of patients performed correct self-care activities three times a week.
CONCLUSION
Post-stroke patients in Saudi Arabia have indicated low levels of medication adherence, while reporting good adherence to their self-care activities. Better adherence was associated with certain patient characteristics such as higher educational level. These findings can help in focusing the efforts to improve adherence and health outcomes for stroke patients in the future.
背景
中风是全球最严重的神经问题之一，被认为是主要死因。由于多种药物治疗和多种疾病并存，中风患者更容易出现药物依从性和自我护理活动水平较低的情况。
方法
招募近期入住公立医院的中风患者。在首席研究员与患者的访谈中，使用经过验证的问卷检查患者的药物依从性，同时也使用一份已开发、验证并先前发表的问卷评估患者的自我护理活动依从性。从患者中探究缺乏依从性的原因。通过患者的医院档案核实患者的详细信息和用药情况。
结果
参与者（n = 173）的平均年龄为53.21岁（标准差 = 8.61）。评估患者的药物依从性显示，超过一半的患者表示他们有时/经常忘记服药，而41.0%的患者有时/经常会不时停药。药物依从性平均得分（满分28分）为18.39（标准差 = 2.1），83.8%的患者依从性较低。发现未服药的患者原因是健忘（46.8%）和服药并发症（20.2%）。更好的依从性与更高的教育水平、更多的疾病数量以及更高的血糖监测频率相关。自我护理活动依从性显示，大多数患者每周进行三次正确的自我护理活动。
结论
沙特阿拉伯的中风后患者药物依从性较低，而自我护理活动依从性良好。更好的依从性与某些患者特征相关，如更高的教育水平。这些发现有助于未来集中精力提高中风患者的依从性和健康结果。
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