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人免疫球蛋白治疗与狼疮抗凝物及抗心磷脂抗体相关的先兆子痫。

Human immunoglobulin therapy for preeclampsia associated with lupus anticoagulant and anticardiolipin antibody.

作者信息

Katz V L, Thorp J M, Watson W J, Fowler L, Heine R P

机构信息

Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill.

出版信息

Obstet Gynecol. 1990 Nov;76(5 Pt 2):986-8.

PMID:2120649
Abstract

A patient with lupus anticoagulant and anticardiolipin antibody developed preeclampsia at 24 weeks' gestation. Therapy with human immunoglobulin (Ig) resulted in stabilization of preeclampsia and suppression of the lupus anticoagulant. Anticardiolipin antibody titers were partially suppressed. Preeclampsia worsened at 32 weeks' gestation, and a healthy infant was delivered. For patients with preeclampsia secondary to lupus anticoagulant before the fetus is viable, human Ig is a potential therapeutic option.

摘要

一名患有狼疮抗凝物和抗心磷脂抗体的患者在妊娠24周时发生了子痫前期。用人免疫球蛋白(Ig)治疗使子痫前期病情稳定,并抑制了狼疮抗凝物。抗心磷脂抗体滴度得到部分抑制。子痫前期在妊娠32周时恶化,随后分娩出一名健康婴儿。对于在胎儿能够存活之前因狼疮抗凝物继发子痫前期的患者,人Ig是一种潜在的治疗选择。

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Obstet Gynecol. 1990 Nov;76(5 Pt 2):986-8.
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