Inokuchi T, Sano K, Kaminogo M
Second Department of Maxillofacial and Oral Surgery, Nagasaki University School of Dentistry, Japan.
Oral Surg Oral Med Oral Pathol. 1990 Sep;70(3):278-81. doi: 10.1016/0030-4220(90)90140-n.
A case of radionecrosis of sphenoid and temporal bones is reported. The patient received a combination of surgery, radiotherapy, and chemotherapy for his left maxillary sinus carcinoma. After the combined therapy, necrosis accompanying inflammation developed in the maxillary and temporal regions. Excision of the necrotic tissues was done, and the left ascending ramus of the mandible was resected because of persistent tumor mass at the left infratemporal fossa. Although the excision wound of the maxilla healed by epithelialization, an area of nonvital bone remained exposed in the temporal region, where progressive osteonecrosis with infection led to breakdown of the skin. The necrotic bones of the zygomatic arch and the sphenotemporal sutural region became visible through the skin defect, and computerized tomography scan revealed bone necrosis involving the inferolateral area and the base of the skull. Excision of the necrotic bone and reconstruction with sternocleidomastoid myocutaneous flap were performed.
报告了一例蝶骨和颞骨放射性坏死病例。该患者因左上颌窦癌接受了手术、放疗和化疗联合治疗。联合治疗后,上颌和颞部出现伴有炎症的坏死。切除了坏死组织,由于左颞下窝持续存在肿瘤肿块,切除了下颌骨的左升支。尽管上颌的切除伤口通过上皮化愈合,但颞部仍有一块无活力的骨暴露在外,此处进行性骨坏死伴感染导致皮肤破溃。通过皮肤缺损可见颧弓和蝶颞缝区域的坏死骨,计算机断层扫描显示颅骨的下外侧区域和底部存在骨坏死。进行了坏死骨切除并用胸锁乳突肌肌皮瓣重建。