Munjal R K, Negi P S, Babu A G, Sinha S N, Anand A K, Kataria T
Rajiv Gandhi Cancer Institute and Research Centre, Rohini, Delhi, India.
J Med Phys. 2006 Apr;31(2):67-71. doi: 10.4103/0971-6203.26690.
Multiple fields in IMRT and optimization allow conformal dose to the target and reduced dose to the surroundings and the regions of interest. Thus we can escalate the dose to the target to achieve better tumor control with low morbidity. Orientation of multiple beams can be achieved by i) different gantry angles, ii) rotating patient's couch isocentrically. In doing so, one or more beam may pass through different materials like the treatment couch, immobilization cast fixation plate, head and neck rest or any other supportive device. Our observations for 6MV photon beam on PRIMUS-KXE2 with MED-TEC carbon fiber tabletop and 10 × 10 cm(2) field size reveals that the maximum dose attenuation by the couch was of the order of 2.96% from gantry angle 120-160°. Attenuation due to cast fixation base plate of PMMA alone was of the order of 5.8-10.55% at gantry angle between 0 and 90°. Attenuation due to carbon fiber base plate alone was 3.8-7.98%. Attenuation coefficient of carbon fiber and PMMA was evaluated and was of the order of 0.082 cm(-1) and 0.064 cm(-1) respectively. Most of the TPS are configured for direct beam incidence attenuation correction factors only. Whereas when the beam is obliquely incident on the couch, base plate, headrest and any other immobilization device get attenuated more than the direct beam incidence. The correction factors for oblique incidence beam attenuation are not configured in most of the commercially available treatment planning systems. Therefore, such high variations in dose delivery could lead to under-dosage to the target volume for treatments requiring multiple fields in IMRT and 3D-CRT and need to be corrected for monitor unit calculations.
调强放疗(IMRT)和优化中的多个射野能使靶区获得适形剂量,同时减少周围组织和感兴趣区域的剂量。因此,我们可以提高靶区剂量,在低并发症的情况下实现更好的肿瘤控制。多束射野的方向可通过以下方式实现:i)不同的机架角度;ii)以等中心旋转患者治疗床。在此过程中,一束或多束射野可能穿过不同的材料,如治疗床、固定模架固定板、头颈部托架或任何其他支撑装置。我们对配备MED-TEC碳纤维桌面且射野尺寸为10×10 cm²的PRIMUS-KXE2上的6MV光子束进行的观察表明,在机架角度120°至160°之间,治疗床导致的最大剂量衰减约为2.96%。在机架角度0°至90°之间,仅聚甲基丙烯酸甲酯(PMMA)的固定模架底板导致的衰减约为5.8%至10.55%。仅碳纤维底板导致的衰减为3.8%至7.98%。评估了碳纤维和PMMA的衰减系数,分别约为0.082 cm⁻¹和0.064 cm⁻¹。大多数治疗计划系统(TPS)仅配置了直射束入射衰减校正因子。然而,当射野倾斜入射到治疗床、底板、头托和任何其他固定装置时,其衰减比直射束入射时更大。大多数商用治疗计划系统未配置斜入射束衰减的校正因子。因此,在IMRT和三维适形放疗(3D-CRT)中需要多个射野的治疗中,如此大的剂量传递差异可能导致靶区体积剂量不足,并且在监测单位计算中需要进行校正。