Badruddin Aamir, Teleb Mohamed S, Abraham Michael G, Taqi Muhammad A, Zaidat Osama O
Department of Neurology, Froedtert & The Medical College of Wisconsin Milwaukee, WI, USA.
Front Neurol. 2010 Oct 12;1:120. doi: 10.3389/fneur.2010.00120. eCollection 2010.
Coexistence of cerebral aneurysm and carotid artery disease may be encountered in clinical practice. Theoretical increase in aneurysmal blood flow may increase risk of rupture if carotid artery disease is treated first. If aneurysm coiling is performed first, stroke risk may increase while repeatedly crossing the diseased artery. It is controversial which disease to treat first, and whether it is safe to treat both simultaneously via endovascular procedures. We document the safety and feasibility of such an approach. Review of collected neurointerventional database at our institution was performed for patients who underwent both carotid artery stenting (CAS) and aneurysm coil embolization (ACE) simultaneously. All patients underwent carotid stenting followed by aneurysm coiling in the same setting. Demographic, clinical data, and outcome measures including success rate and periprocedural complications were collected. Five hundred and ninety aneurysms coiling were screened for patients who underwent combined CAS and ACE. Ten patients were identified. Mean age was 67.7 years (range 51-89). The success rate for stenting and coiling was 100% with no immediate complications. The coiling procedure time was extended by an average of 45 min for performing both procedures jointly. No stroke, TIAs, or aneurysmal rebleeding was found on their most recent follow up. Our case series demonstrates that it is safe and feasible to perform CAS and ACE simultaneously as one procedure which may avoid unwanted risk of treating either disease at two separate time sessions.
在临床实践中可能会遇到脑动脉瘤与颈动脉疾病并存的情况。如果先治疗颈动脉疾病,理论上动脉瘤血流增加可能会增加破裂风险。如果先进行动脉瘤栓塞,在反复穿过病变动脉时中风风险可能会增加。先治疗哪种疾病以及通过血管内手术同时治疗两种疾病是否安全存在争议。我们记录了这种方法的安全性和可行性。对我们机构收集的神经介入数据库进行回顾,筛选出同时接受颈动脉支架置入术(CAS)和动脉瘤弹簧圈栓塞术(ACE)的患者。所有患者在同一环境下先进行颈动脉支架置入术,然后进行动脉瘤弹簧圈栓塞术。收集人口统计学、临床数据以及包括成功率和围手术期并发症在内的结果指标。对接受CAS和ACE联合治疗的患者筛查了590例动脉瘤弹簧圈栓塞术。确定了10例患者。平均年龄为67.7岁(范围51 - 89岁)。支架置入术和弹簧圈栓塞术的成功率为100%,无即刻并发症。联合进行这两种手术时,弹簧圈栓塞术的操作时间平均延长了45分钟。在最近的随访中未发现中风、短暂性脑缺血发作或动脉瘤再出血。我们的病例系列表明,将CAS和ACE作为一个手术同时进行是安全可行的,这可能避免在两个不同时间段分别治疗两种疾病带来的不必要风险。