Department of Diagnostic Radiology, University of Texas MD Anderson Cancer Center, Houston, TX 77030-4009, USA.
Skeletal Radiol. 2011 May;40(5):641-5. doi: 10.1007/s00256-010-1079-x. Epub 2011 Jan 5.
We describe the imaging and pathological features of a rare case of sacral hibernoma that was discovered incidentally in a patient with low back pain. The benign-appearing, small intraosseous lesion in the sacrum was sclerotic on CT. MRI revealed that the lesion was heterogeneously hyperintense on T1W (lower in intensity than subcutaneous fat) and heterogeneously hypointense on fat-saturated T2W and STIR images. It showed mild heterogeneous enhancement on the post-contrast fat-saturated T1 MR images due to increased vascularity. A biopsy of the lesion was performed. The biopsy specimen demonstrated multivacuolated cells with immunohistochemical features of brown adipose tissue consistent with hibernoma.
我们描述了一例罕见的骶骨冬眠瘤的影像学和病理学特征,该肿瘤是在一位腰痛患者中偶然发现的。骶骨内小的良性表现的骨内病变在 CT 上呈硬化性。MRI 显示病变在 T1W 上呈不均匀高信号(比皮下脂肪信号低),在脂肪饱和 T2W 和 STIR 图像上呈不均匀低信号。由于血管增多,病变在增强后脂肪饱和 T1 MR 图像上呈轻度不均匀强化。对病变进行了活检。活检标本显示多泡细胞,免疫组化显示为棕色脂肪组织特征,符合冬眠瘤。