Indiana University, Simon Cancer Center, Department of Ob-Gyn, Indianapolis, Indiana 46202, USA.
Semin Reprod Med. 2011 Jan;29(1):55-60. doi: 10.1055/s-0030-1268704. Epub 2011 Jan 4.
Uterus transplantation for absolute uterus factor infertility is moving closer to human trials. The indication for uterus transplantation is evident as is its potential to ameliorate the social and personal burdens of these patients. The extensive collaborative research efforts between animal works, advancements in transplantation medicine, and immune suppression have culminated in demonstrating its apparent feasibility. As for the concerns regarding its risk, in perspective it is similar to other high-risk pregnancies. Moving uterus transplantation toward clinical applications obviously will require a continued commitment of research and support.
子宫移植治疗因子宫因素导致的不孕正逐步进入临床试验阶段。子宫移植适应证明确，且有潜力减轻此类患者的社会和个人负担。动物实验、移植医学进步和免疫抑制方面的广泛合作研究，最终证明了其明显的可行性。至于对其风险的担忧，从长远来看，它与其他高危妊娠类似。将子宫移植推向临床应用显然需要持续的研究和支持。
