Suganuma Nobuhiko, Hayashi Ayako, Kisu Iori, Banno Kouji, Hara Hisako, Mihara Makoto
Project Team for Uterus Transplantation Japan.
Department of Human Health Sciences Kyoto University Graduate School of Medicine Kyoto Japan.
Reprod Med Biol. 2017 Aug 6;16(4):305-313. doi: 10.1002/rmb2.12048. eCollection 2017 Oct.
In recent years, uterus transplantation (UTx) has been applied as the treatment for patients with uterine factor infertility worldwide. Thus, the clinical application of UTx in Japan should be considered through both the history of UTx technology development in the world and future prospects.
Recent information on UTx was collected via a literature survey and the Internet.
Basic research using various animals has been done mainly since 2000. In 2014, the world's first UTx baby was born in Sweden. In total, 24 UTx procedures have been performed at 10 institutes in nine countries and five births were obtained (as of May, 2017). In Japan, the "Project Team for Uterus Transplantation" initiated UTx experiments in 2008 and the "Japan Society for Uterus Transplantation" was organized in March, 2014. In the rest of the world, the "International Society for Uterus Transplantation" was established in January, 2016.
Uterus transplantation is still under development as a reproductive medicine tool and organ transplant procedure. A collaborative system that is not limited by facilities and specialties should strive to build an "all-Japan" team.
近年来，子宫移植（UTx）已在全球范围内应用于治疗子宫因素导致的不孕症患者。因此，应通过子宫移植技术在世界范围内的发展历史和未来前景来考虑其在日本的临床应用。
通过文献调查和互联网收集有关子宫移植的最新信息。
主要自2000年以来已使用各种动物进行了基础研究。2014年，世界上首例子宫移植婴儿在瑞典出生。截至2017年5月，九个国家的10家机构共进行了24例子宫移植手术，并获得了5例分娩。在日本，“子宫移植项目团队”于2008年启动了子宫移植实验，并于2014年3月成立了“日本子宫移植学会”。在世界其他地区，“国际子宫移植学会”于2016年1月成立。
子宫移植作为一种生殖医学工具和器官移植手术仍在发展中。一个不受设施和专业限制的协作系统应努力组建一个“全日本”团队。
