Jez Wacław, Irzyniec Tomasz
Slaski Uniwersytet Medyczny w Katowicach, Zakład Promocji Zdrowia i Pielegniarstwa Srodowiskowego.
Pol Merkur Lekarski. 2010 Oct;29(172):247-9.
Turner's syndrome is a chromosomal anomaly which occurs in approximately one in 2500 females. The syndrome is characterized by the presence of primary gonadal dysgenesia which is manifested by, among others, amenorrhoea. Taking this fact into consideration, the values of blood cell count in Turner's syndrome women could have been expected to be better than the corresponding values in the general population of women. The aim of the present research is to evaluate the basics haematology parameters in women with Turner's syndrome.
Basic parameters of blood cell count were marked in 176 women with Turner's syndrome. One hundred and three subjects were found to have X monosomy, whereas the rest of the females had other types of karyotype. The results obtained were compared to the corresponding parameters in the general population of Polish women.
There were no statistically significant differences between subjects with Turner's syndrome and general female population as far as the white blood system and the red blood system parameters were concerned. Similarly, the thrombocyte count failed to be significantly different in women with Turner's syndrome and in healthy women. However, Turner's syndrome subjects with 45, X karyotype, compared to females with other karyotypes, showed a significantly higher number of thrombocytes: 267.5 +/- 70 vs 240.1 +/- 69 thousand/mm3. CONCLUSIONS. 1. Basic parameters of peripheral blood count in women with Turner's syndrome do not differ from the reference values in general female population. 2. Turner's syndrome subjects with X monosomy are characterized by a significantly higher number of thrombocytes than other women.
特纳综合征是一种染色体异常疾病，约每2500名女性中就有1例发病。该综合征的特征是原发性性腺发育不全，表现为闭经等症状。考虑到这一事实，预计特纳综合征女性的血细胞计数会优于普通女性群体的相应数值。本研究的目的是评估特纳综合征女性的基础血液学参数。
对176例特纳综合征女性的血细胞计数基础参数进行了记录。其中103例受试者为X单体型，其余女性具有其他类型的核型。将所得结果与波兰普通女性群体的相应参数进行比较。
就白细胞系统和红细胞系统参数而言，特纳综合征患者与普通女性群体之间无统计学显著差异。同样，特纳综合征女性与健康女性的血小板计数也无显著差异。然而，与其他核型的女性相比，具有45,X核型的特纳综合征患者血小板数量显著更高：267.5±70对240.1±69千/mm³。结论。1. 特纳综合征女性外周血细胞计数的基础参数与普通女性群体的参考值无差异。2. X单体型的特纳综合征患者血小板数量显著高于其他女性。
