[The values of peripheral blood cell count parameters in women with Turner's syndrome].

UNLABELLED

Turner's syndrome is a chromosomal anomaly which occurs in approximately one in 2500 females. The syndrome is characterized by the presence of primary gonadal dysgenesia which is manifested by, among others, amenorrhoea. Taking this fact into consideration, the values of blood cell count in Turner's syndrome women could have been expected to be better than the corresponding values in the general population of women. The aim of the present research is to evaluate the basics haematology parameters in women with Turner's syndrome.

MATERIAL AND METHODS

Basic parameters of blood cell count were marked in 176 women with Turner's syndrome. One hundred and three subjects were found to have X monosomy, whereas the rest of the females had other types of karyotype. The results obtained were compared to the corresponding parameters in the general population of Polish women.

RESULTS

There were no statistically significant differences between subjects with Turner's syndrome and general female population as far as the white blood system and the red blood system parameters were concerned. Similarly, the thrombocyte count failed to be significantly different in women with Turner's syndrome and in healthy women. However, Turner's syndrome subjects with 45, X karyotype, compared to females with other karyotypes, showed a significantly higher number of thrombocytes: 267.5 +/- 70 vs 240.1 +/- 69 thousand/mm3. CONCLUSIONS. 1. Basic parameters of peripheral blood count in women with Turner's syndrome do not differ from the reference values in general female population. 2. Turner's syndrome subjects with X monosomy are characterized by a significantly higher number of thrombocytes than other women.