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[Study of correlation factors with left ventricular hypertrophy during cardiac hypertrophy induced hypertension and regression in rats].

作者信息

Li Hai-ying, Liu Zi-quan, Tong Chang-qing, Qi Li

机构信息

Department of physiology, Medical College of the Chinese People's Armed Police Forces, Tianjin 300162, China.

出版信息

Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2003 May;19(2):127-30.

PMID:21207656
Abstract

AIM

To investigate the relations between left ventricular hypertrophy and systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), neuropeptide Y (NPY) during cardiac hypertrophy and regression.

METHODS

Blood pressure and heart rate were recorded with polygraph channel biologic message system. NPY in plasma and myocardium were measured with Radioimmunoassay. Correlation coefficient were calculated with SPSS software.

RESULTS

There were positive correlations between SBP, DBP, MAP, NPY in the cardiac tissue and cardiac coefficient (LVW/BW). There was no correlations between cardiac coefficient and heart rate (HR), NPY in plasma.

CONCLUSION

Hypertension is one of cardiac hypertrophy factors, SBP correlate better with LVW/ BW than DBP. SBP, DBP, MAP, NPY in cardiac tissue has correlative tendency with LVW/BW.

摘要

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