Croucher Institute for Environmental Sciences, and Department of Biology, Hong Kong Baptist University, Hong Kong, PR China.
Environ Sci Technol. 2011 Feb 15;45(4):1630-7. doi: 10.1021/es102444g. Epub 2011 Jan 5.
The objective of this study was to quantify organic chlorinated pesticides (OCPs), polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), and polycyclic aromatic hydrocarbons (PAHs) in blood plasma collected from 111 healthy residents in Hong Kong to assess the levels of these pollutants in the general population during the period of March to April, 2008. Concentrations of these residues in blood plasma obtained from the Hong Kong Red Cross Blood Transfusion Service were determined by gas chromatography-mass spectrometry. Naphthalene, phenanthrene, p,p'-DDE, PCB-180, and PBDE-47 were detected in 100% of the participants. Females had significantly greater concentrations of acenaphthylene (female: 93.3 ng/g lipid; male: 39.8, p < 0.05), anthracene (22.3; 15.3, p < 0.05), fluoranthene (138; 125, p < 0.05), p,p'-DDE, p,p'-DDT, PCB-183, BDE-99 than males. Blood of smokers contained significantly greater (p < 0.05) concentrations of acenaphthene, benzo(a)pyrene, p,p'-DDE, p,p'-DDT, PCB-138, BDE-47, and BDE-99 than did blood of nonsmokers. Positive correlations were found between concentrations of each class of pollutant, with respect to seafood diet habit, Body Mass Index (BMI), and age. Concentrations of HCHs and DDTs in blood plasma of healthy Hong Kong residents were greater than those of other countries, and it was found that smoking, consumption of a seafood diet, BMI, and age could influence concentrations in human blood.
本研究的目的是量化 2008 年 3 月至 4 月期间采集的 111 名香港健康居民血液血浆中的有机氯农药（OCPs）、多氯联苯（PCBs）、多溴联苯醚（PBDEs）和多环芳烃（PAHs），以评估该时期普通人群中这些污染物的水平。从香港红十字会献血服务中心采集的血液血浆中这些残留物的浓度是通过气相色谱-质谱法确定的。100%的参与者血液中都检测到萘、菲、p,p'-DDE、PCB-180 和 PBDE-47。女性血液中苊烯（女性：93.3ng/g 脂质；男性：39.8，p<0.05）、蒽（22.3；15.3，p<0.05）、荧蒽（138；125，p<0.05）、p,p'-DDE、p,p'-DDT、PCB-183、BDE-99 的浓度明显大于男性。吸烟者血液中苊、苯并（a）芘、p,p'-DDE、p,p'-DDT、PCB-138、BDE-47 和 BDE-99 的浓度明显高于不吸烟者（p<0.05）。发现每一类污染物的浓度与海鲜饮食习惯、体重指数（BMI）和年龄之间存在正相关关系。香港健康居民血液血浆中的 HCHs 和 DDTs 浓度高于其他国家，发现吸烟、海鲜饮食、BMI 和年龄会影响人血液中的浓度。
