Tongprasert Fuanglada, Srisupundit Kasemsri, Luewan Suchaya, Tongsong Theera
Department of Obstetrics and Gynecology, Faculty of Medicine Chiang Mai University, Thailand.
J Clin Ultrasound. 2011 Feb;39(2):74-7. doi: 10.1002/jcu.20756. Epub 2010 Nov 12.
To create a normal reference table of fetal liver length in normal fetuses
A prospective, cross-sectional study was conducted on normal pregnancies with accurate gestational age (GA) from 14 to 40 weeks of gestation. All fetuses were measured for fetal liver length from the top of the right hemidiaphragm to tip of the right liver lobe on coronal image of the fetal abdomen, using high-resolution real-time ultrasound with a 2- to 4-MHz convex transducer.
A total of 685 normal pregnant women between 14 and 40 weeks of gestation were recruited. Forty-five were excluded due to poor image quality and fetal abnormalities. The remaining 640 were available for analysis. The linear regression model was best fitted to estimate the 5th, 50th, and 95th percentile range of liver length at each gestational week. Fetal liver length was gradually increased with GA with fitted equation as follows: Liver length (mm) = 1.61 (GA, week) - 6.75 (r(2) = 0.94, p < 0.001).
A normal reference range of fetal liver length for each GA between 14 and 40 weeks was constructed. This may be a useful tool in assessment for some fetal pathologic conditions, especially when fetal anemia is suspected.
建立正常胎儿肝脏长度的正常参考表
对妊娠14至40周、孕周准确的正常妊娠进行前瞻性横断面研究。使用2至4MHz凸阵探头的高分辨率实时超声，在胎儿腹部冠状图像上测量所有胎儿从右半膈顶部至右肝叶尖端的肝脏长度。
共纳入685例妊娠14至40周的正常孕妇。45例因图像质量差和胎儿异常被排除。其余640例可供分析。线性回归模型最适合估计每个孕周肝脏长度的第5、第50和第95百分位数范围。胎儿肝脏长度随孕周逐渐增加，拟合方程如下：肝脏长度（mm）=1.61（孕周，周）-6.75（r²=0.94，p<0.001）。
构建了妊娠14至40周各孕周胎儿肝脏长度的正常参考范围。这可能是评估某些胎儿病理状况的有用工具，尤其是怀疑胎儿贫血时。
