Children's Hospital Boston and Harvard Medical School, Boston, Massachusetts 02215, USA.
Urology. 2011 Mar;77(3):576-80. doi: 10.1016/j.urology.2010.10.016. Epub 2011 Jan 7.
To examine the prevalence and correlates of general and bladder pain syndrome/interstitial cystitis (BPS/IC)-specific sexual dysfunction among women in the RAND Interstitial Cystitis Epidemiology study using a probability sample survey of U.S. households. Sexual dysfunction can contribute to a reduced quality of life for women with bladder pain syndrome/interstitial cystitis (BPS/IC).
We telephoned 146,231 households to identify women who reported bladder symptoms or a BPS/IC diagnosis. Those who reported either underwent a second-stage screening using the RAND Interstitial Cystitis Epidemiology study high-specificity symptom criteria. The criteria were pain, pressure, or discomfort in pelvic area; daytime urinary frequency ≥10 times or urgency due to pain, pressure, or discomfort (not fear of wetting); pain that worsened as the bladder filled; bladder symptoms did not resolve after antibiotic treatment; and patients never treated with hormone injections for endometriosis. Women who met the RAND Interstitial Cystitis Epidemiology criteria (n = 1469) completed measures of BPS/IC-specific and general sexual dysfunction symptoms, bladder symptom severity, general physical health, depression, medical care-seeking, and sociodemographic characteristics.
Of those with a current sexual partner (75%), 88% reported ≥1 general sexual dysfunction symptom and 90% reported ≥1 BPS/IC-specific sexual dysfunction symptom in the past 4 weeks. In the multivariate models, BPS/IC-specific sexual dysfunction was significantly associated with more severe BPS/IC symptoms, younger age, worse depression symptoms, and worse perceived general health. Multivariate correlates of general sexual dysfunction included non-Latino race/ethnicity, being married, and having depression symptoms.
The results of our study have shown that women with BPS/IC symptoms experience very high levels of sexual dysfunction. Also, sexual dysfunction covaries with symptoms.
使用美国家庭概率抽样调查,研究 RAND 间质性膀胱炎流行病学研究中的女性普遍存在和膀胱疼痛综合征/间质性膀胱炎(BPS/IC)特异性性功能障碍的患病率及其相关因素。性功能障碍可能会降低患有膀胱疼痛综合征/间质性膀胱炎(BPS/IC)的女性的生活质量。
我们致电 146231 户家庭,以确定报告有膀胱症状或 BPS/IC 诊断的女性。那些报告有上述症状的女性接受了第二阶段的筛选,使用 RAND 间质性膀胱炎流行病学研究的高特异性症状标准。这些标准包括骨盆区域疼痛、压迫或不适;白天排尿频率≥10 次或因疼痛、压迫或不适而出现尿急(不是害怕淋湿);膀胱充盈时疼痛加剧;抗生素治疗后膀胱症状未缓解;以及从未接受过激素注射治疗子宫内膜异位症的患者。符合 RAND 间质性膀胱炎流行病学标准的女性(n=1469)完成了 BPS/IC 特异性和一般性功能障碍症状、膀胱症状严重程度、一般身体健康、抑郁、寻求医疗护理以及社会人口统计学特征的评估。
在有当前性伴侣的女性中(75%),88%报告在过去 4 周内有≥1 种一般性功能障碍症状,90%报告有≥1 种 BPS/IC 特异性性功能障碍症状。在多变量模型中,BPS/IC 特异性性功能障碍与更严重的 BPS/IC 症状、更年轻的年龄、更严重的抑郁症状和更差的总体健康感知显著相关。一般性功能障碍的多变量相关因素包括非拉丁裔种族/民族、已婚和抑郁症状。
我们的研究结果表明,有 BPS/IC 症状的女性经历了非常高水平的性功能障碍。此外,性功能障碍与症状相关。