Department of Veterinary Clinical Sciences, The Royal Veterinary College, University of London, Hawkshead Lane, North Mymns, Hatfield, Hertfordshire AL9 7TA, UK.
Vet J. 2011 Dec;190(3):359-63. doi: 10.1016/j.tvjl.2010.12.002. Epub 2011 Jan 8.
Chiari-like malformation (CM) and syringomyelia (SM) is an important disease complex in the Cavalier King Charles Spaniel (CKCS) but data about the anatomical distribution of SM along the spinal cord are lacking in veterinary medicine. The objective of this study was to define the anatomic distribution of SM in CKCS clinically affected by CM/SM. Magnetic resonance imaging (MRI) of the brain and the entire spinal cord of 49 dogs was performed and different morphological parameters compared. Syrinx formation was present in the C1-C4 region and in other parts of the spinal cord. The maximal dorsoventral syrinx size can occur in any region of the spinal cord and the total syrinx size was positively correlated with age. Seventy-six per cent of CKCS with a cranial cervical syrinx also have a syrinx affecting more caudal spinal cord regions. MRI restricted to the cervical region may underestimate the extent of SM and the severity of the disease process in the majority of dogs.
Chiari 样畸形（CM）和脊髓空洞症（SM）是查理王小猎犬（CKCS）中的一种重要疾病，但兽医领域缺乏关于 SM 在脊髓中的解剖分布的数据。本研究的目的是定义临床受 CM/SM 影响的 CKCS 中 SM 的解剖分布。对 49 只狗的大脑和整个脊髓进行了磁共振成像（MRI）检查，并比较了不同的形态参数。在 C1-C4 区域和脊髓的其他部位形成了空洞。最大的脊髓背侧-腹侧空洞大小可发生在脊髓的任何区域，并且总空洞大小与年龄呈正相关。76%的颅颈脊髓空洞症 CKCS 也有脊髓空洞症影响更尾部的脊髓区域。仅对颈椎进行 MRI 可能会低估大多数狗的 SM 范围和疾病严重程度。
