Gaggero R, Ferraris P C, De Negri M
Istituto G. Gaslini, Università di Genova, Italy.
Neuropediatrics. 1990 Aug;21(3):143-5. doi: 10.1055/s-2008-1071482.
In two children affected with "Epilepsia Partialis Continua" (EPC) of progressive type, probably secondary to a slow encephalitis, the percentage of T-lymphocytes in CSF was lower than normal (30% compared to 90%). The CSF-T-lymphocytes are characterized by their ability to form E-rosettes. In one patient signs of intrathecal synthesis of IgG, especially oligoclonal bands at isoelectrofocusing, were observed. These results confirm, that in this type of EPC some immunological parameters in the CSF are impaired; so the aetiological hypothesis of an infectious disease, caused by a non-conventional viral agent, is supported.
在两名患有进行性“持续性部分性癫痫”（EPC）的儿童中，病因可能是慢脑炎，其脑脊液中T淋巴细胞的百分比低于正常水平（分别为30%和90%）。脑脊液中的T淋巴细胞以其形成E花环的能力为特征。在一名患者中，观察到脑脊液中有IgG鞘内合成的迹象，特别是等电聚焦时的寡克隆带。这些结果证实，在这类EPC中，脑脊液中的一些免疫参数受到损害；因此，由非常规病毒病原体引起的传染病病因假说得到了支持。
