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泌尿外科手术中注射亚甲蓝后动脉血氧饱和度假性降低和高铁血红蛋白血症

False indication of arterial oxygen desaturation and methemoglobinemia following injection of methylene blue in urological surgery.

作者信息

Kirlangitis J J, Middaugh R E, Zablocki A, Rodriquez F

机构信息

Department of Surgery, Brooke Army Medical Center, Fort Sam Houston, TX 78234-6200.

出版信息

Mil Med. 1990 Jun;155(6):260-2.

PMID:2122301
Abstract

The pulse oximeter serves as an indicator of arterial oxygen saturation. We present two cases in which methylene blue injection during urological surgery appeared to cause arterial oxygen desaturation by pulse oximetry and methemoglobinemia by arterial blood gas co-oximetry. Methylene blue interferes with light absorption and gives a false estimate of the percentage of oxyhemoglobin and arterial oxygen saturation. The co-oximeter interprets methylene blue as methemoglobin and gives a false indication of methemoglobinemia. The surgical team must be familiar with conditions and agents that interfere with their ability to safely monitor surgical patients.

摘要

脉搏血氧仪可作为动脉血氧饱和度的指标。我们报告两例泌尿外科手术中注射亚甲蓝后,经脉搏血氧测定法显示动脉氧饱和度下降,经动脉血气共血氧测定法显示出现高铁血红蛋白血症的病例。亚甲蓝会干扰光吸收,从而对氧合血红蛋白百分比和动脉血氧饱和度给出错误估计。共血氧测定仪将亚甲蓝解读为高铁血红蛋白,并给出高铁血红蛋白血症的错误指示。手术团队必须熟悉那些会干扰其安全监测手术患者能力的情况和药物。

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