Rone J K, Friedstrom S
Department of Internal Medicine, USAF Medical Center Keesler, Biloxi, MS 39534.
Mil Med. 1990 Jun;155(6):272-4.
Typhoid vaccination is part of the routine immunization of all military personnel on mobility status. We report the cases of Air Force students who presented to our facility with presumed systemic reactions to the typhoid vaccine much more severe than those commonly reported. Review of the literature reveals that an influenza-like reaction of variable severity commonly occurs in these patients, and in addition there are isolated reports of more severe reactions. These findings shed doubt on the overall safety of the currently used vaccine and warrant a consideration of its abandonment. Several safer alternatives, including the new live oral vaccine used in Europe, are discussed.
伤寒疫苗接种是所有处于流动状态军事人员常规免疫的一部分。我们报告了空军学员的病例，他们来到我们机构，表现出对伤寒疫苗的推测性全身反应，比通常报告的反应严重得多。文献回顾显示，这些患者通常会出现严重程度不一的流感样反应，此外还有关于更严重反应的个别报告。这些发现对目前使用疫苗的整体安全性提出了质疑，有必要考虑放弃使用该疫苗。文中还讨论了几种更安全的替代方案，包括欧洲使用的新型口服活疫苗。
