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曼氏血吸虫感染:一种免疫复合物病,表现为多发性关节炎。

Schistosoma mansoni infection: an immune complex disease presenting with polyarthritis.

机构信息

Rheumatology Unit, Department of Medicine, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil.

出版信息

Rheumatol Int. 2013 May;33(5):1341-3. doi: 10.1007/s00296-010-1562-7. Epub 2011 Jan 13.

DOI:10.1007/s00296-010-1562-7
PMID:21229360
Abstract

Schistosomiasis or bilharzia is a parasitic disease found in tropical countries. Most infections are subclinical but may progress to chronic form characterized most frequently by the presence of liver involvement and portal hypertension. We report a patient that presented chronic polyarthritis with positive rheumatoid factor. During investigation, increased liver enzymes, negative hepatitis serologies and signs of portal hypertension on an ultrasound examination raised suspicion of S. mansoni infection. We will discuss pathophysiology and clinical manifestations of S. mansoni infection with special attention to articular involvement.

摘要

血吸虫病或血丝虫病是一种在热带国家发现的寄生虫病。大多数感染是无症状的,但可能会进展为慢性形式,其特征通常是存在肝脏受累和门脉高压。我们报告了一例表现为慢性多发性关节炎且类风湿因子阳性的患者。在检查过程中,肝酶升高、肝炎血清学阴性和超声检查有门脉高压的迹象,引起了对曼氏血吸虫感染的怀疑。我们将讨论曼氏血吸虫感染的病理生理学和临床表现,特别注意关节受累。

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Rheumatol Int. 2013 May;33(5):1341-3. doi: 10.1007/s00296-010-1562-7. Epub 2011 Jan 13.
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本文引用的文献

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Schistosomiasis mansoni -- clinical features.曼氏血吸虫病——临床特征
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Schistosomiasis.血吸虫病
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The pathogenesis of arthropathy in experimental Schistosomiasis mansoni.实验性曼氏血吸虫病关节病的发病机制
肺动脉高压的性别差异:感染和自身免疫在疾病发病机制中的作用。
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Natural killer cells (NK) and antibody-dependent cell-mediated cytotoxicity (ADCC) components of Schistosoma mansoni infection.
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Treatment of patients with schistosomiasis mansoni: a double blind clinical trial comparing praziquantel with oxamniquine.曼氏血吸虫病患者的治疗:吡喹酮与羟氨喹对比的双盲临床试验
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Schistosomiasis and inflammatory polyarthritis: a clinical, radiological and laboratory study of 96 patients infected by S. mansoni with particular reference to the diarthrodial joint.血吸虫病与炎性多关节炎:对96例曼氏血吸虫感染患者的临床、放射学及实验室研究,特别关注滑膜关节
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10
Immune complex arthritis in a patient with Schistosoma mansoni infection.一名曼氏血吸虫感染患者的免疫复合物性关节炎。
Arthritis Rheum. 1986 Feb;29(2):296-9. doi: 10.1002/art.1780290220.