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Natural killer cells (NK) and antibody-dependent cell-mediated cytotoxicity (ADCC) components of Schistosoma mansoni infection.

作者信息

Attallah A M, Lewis F A, Urritia-Shaw A, Folks T, Yeatman T J

出版信息

Int Arch Allergy Appl Immunol. 1980;63(3):351-4. doi: 10.1159/000232649.

DOI:10.1159/000232649
PMID:7419296
Abstract

Schistosoma mansoni cercariae were used to infect CBA-J mice, a strain characterized by possessing a high level of NK cells. 4 days after infection with cercariae, the natural cytotoxic capacity of these mice, as measured by NK and ADCC, reached a peak level of enhancement significantly greater than that of uninfected controls. Infection by this parasite appears to activate natural cell-mediated immune defense systems. Further observation of the pattern of response of NK and ADCC effector cells to infection by cercariae may reveal important information regarding the inherent immunity to the schistosome infection.

摘要

相似文献

1
Natural killer cells (NK) and antibody-dependent cell-mediated cytotoxicity (ADCC) components of Schistosoma mansoni infection.
Int Arch Allergy Appl Immunol. 1980;63(3):351-4. doi: 10.1159/000232649.
2
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Differences in adult Schistosoma mansoni worm burden requirements for the establishment of resistance to reinfection in inbred mice. I. CBA/J and C57BL/6 mice.近交系小鼠建立曼氏血吸虫再感染抗性所需成虫虫荷的差异。I. CBA/J和C57BL/6小鼠
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Suppressor T cells in the specific control of the carrier response to schistosomula in mice infected with Schistosoma mansoni.在感染曼氏血吸虫的小鼠中，抑制性T细胞对童虫反应的特异性调控。
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