Ma J, Turan A
School of Mechanical, Aerospace and Civil Engineering, The University of Manchester, UK.
Comput Methods Biomech Biomed Engin. 2011 Aug;14(8):683-94. doi: 10.1080/10255842.2010.493514. Epub 2011 May 24.
Numerical prediction of non-Newtonian blood flow in a 3D abdominal aortic aneurysm bifurcating model is carried out. The non-Newtonian Carreau model is used to characterise the shear thinning behaviour of the human blood. A physical inlet velocity waveform incorporating a radial velocity distribution reasonably representative of a practical case configuration is employed. Case studies subject to both equal and unequal outlet pressures at iliac bifurcations are presented to display convincingly the downstream pressure influences on the flow behaviour within the aneurysm. Simulations indicate that the non-Newtonian aspects of the blood cannot at all be neglected or given a cursory treatment. The wall shear stress (WSS) is found to change significantly at both the proximal and distal ends of the aneurysm. At the peak systole, the WSS is peak around the bifurcation point, whereas the WSS becomes zero in the bifurcation point. Differential downstream pressure fields display significant effects regarding the flow evolution in the iliac arteries, whereas little or no effects are observed directly on the flow details in the aneurysm.
对三维腹主动脉瘤分叉模型中的非牛顿血流进行了数值预测。采用非牛顿卡雷奥模型来描述人体血液的剪切变稀行为。使用了一种物理入口速度波形,该波形包含合理代表实际情况配置的径向速度分布。给出了在髂动脉分叉处出口压力相等和不相等情况下的案例研究,以令人信服地展示下游压力对动脉瘤内血流行为的影响。模拟表明,血液的非牛顿特性根本不能被忽视或草率处理。发现动脉瘤近端和远端的壁面剪应力(WSS)有显著变化。在收缩期峰值时,WSS在分叉点附近达到峰值,而在分叉点处WSS变为零。不同的下游压力场对髂动脉中的血流演变显示出显著影响,而对动脉瘤内的血流细节几乎没有直接影响。