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营养与前列腺癌

Nutrition and prostate cancer.

作者信息

Vlajinac H, Ilic M, Marinkovic J, Sipetic S

机构信息

Institute of Epidemiology, School of Medicine, University of Belgrade, Belgrade, Serbia.

出版信息

J BUON. 2010 Oct-Dec;15(4):698-703.

Abstract

PURPOSE

since an association between prostate cancer and some foods or food groups like meat, milk and dairy products, tomato foods, and allium vegetables, has been suggested, we analyzed the possibility that some food items or some food groups could be related to prostate cancer in some other way and not only through their nutrients. The purpose of this study was to test some hypotheses about diet as risk factor for prostate cancer.

METHODS

this case-control study comprised 101 cases of prostate cancer and 202 hospital controls individually matched for age (± 2 years), hospital admission and place of residence. Dietary information of 150 food items was obtained by a quantitative history approach.

RESULTS

multivariate logistic regression analysis indicated as risk factors for prostate cancer high intake of fruit, processed meat, fish (most frequently canned) and butter. High intake of chicken, potato and rice exhibited a protective effect.

CONCLUSION

these results support the hypothesis that consumption of meat and fat play a role in the development of prostate cancer. The findings that consumption of processed meat only (not fresh) and fish increased the risk of prostate cancer, as well as the protective effect of chicken, potato and rice consumption should be corroborated by other investigators.

摘要

目的

由于已有研究表明前列腺癌与某些食物或食物类别(如肉类、牛奶及奶制品、番茄类食物和葱属蔬菜)之间存在关联,我们分析了某些食物项目或食物类别可能以其他方式而非仅通过其营养成分与前列腺癌相关的可能性。本研究的目的是检验一些关于饮食作为前列腺癌风险因素的假设。

方法

这项病例对照研究包括101例前列腺癌患者和202名医院对照者,后者在年龄(±2岁)、入院情况和居住地点方面与病例进行个体匹配。通过定量饮食史方法获取了150种食物项目的饮食信息。

结果

多因素逻辑回归分析表明,水果、加工肉类、鱼类(最常见的是罐装鱼)和黄油的高摄入量是前列腺癌的风险因素。鸡肉、土豆和大米的高摄入量具有保护作用。

结论

这些结果支持了肉类和脂肪的摄入在前列腺癌发生过程中起作用这一假设。仅加工肉类(而非新鲜肉类)和鱼类的摄入会增加前列腺癌风险,以及鸡肉、土豆和大米的摄入具有保护作用这一发现,应由其他研究者进行验证。

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