血小板激活中的 P2Y12 受体。
P2Y12 receptor in platelet activation.
机构信息
Department of Physiology, Temple University School of Medicine, Philadelphia, PA, USA.
出版信息
Platelets. 2011;22(1):56-60. doi: 10.3109/09537104.2010.497231.
PMID:21231822
Abstract
ADP plays an important role in hemostasis and thrombosis. The P2Y12 receptor, activated by ADP, plays a central role in platelet activation and thrombus formation. Thus, the P2Y12 receptor has been an effective target for antithrombotic drugs.
摘要
ADP 在止血和血栓形成中起着重要作用。ADP 激活的 P2Y12 受体在血小板激活和血栓形成中起着核心作用。因此，P2Y12 受体已成为抗血栓药物的有效靶点。
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