Department of Chemistry, Zhejiang University, Hangzhou, P R China.
Chem Commun (Camb). 2011 Mar 7;47(9):2628-30. doi: 10.1039/c0cc04875e. Epub 2011 Jan 13.
Phenalenone derivatives were efficiently constructed from 1,8-diiodonaphthalene and tertiary propynols via a one-pot domino reaction which eventually included Pd-catalyzed Sonogoshira coupling, Pd-catalyzed allylic oxidation and Pd-catalyzed C(sp(2))-H activation. Moreover, the synthesized phenalenone derivative presented a practical application as a fluorescent chemosensor for fluoride anion with high sensitivity and selectivity.
菲咯啉酮衍生物可由 1,8-二碘萘和三级丙炔醇通过一锅多米诺反应高效构建，该反应最终包括 Pd 催化的 Sonogoshira 偶联、Pd 催化的烯丙基氧化和 Pd 催化的 C(sp(2))-H 活化。此外，合成的菲咯啉酮衍生物可用作对氟离子具有高灵敏度和选择性的荧光化学传感器。
