一种水溶性 C60-卟啉化合物，可实现高效 DNA 光解。
A water-soluble C60-porphyrin compound for highly efficient DNA photocleavage.
机构信息
College of Chemistry, Sichuan University, Chengdu, China.
出版信息
Chem Commun (Camb). 2011 Mar 14;47(10):2982-4. doi: 10.1039/c0cc04919k. Epub 2011 Jan 14.
PMID:21234484
Abstract
A water-soluble covalently linked C(60)-porphyrin compound-C(60)Por is reported to show enhanced DNA-cleaving activity. The highly enhanced DNA-cleaving activity is expected to be ascribed to the high water-solubility and affinity of C(60)Por to DNA, as well as to the accessibility to the charge-separated states C(60)˙(-)-Por˙(+) formed under radiation.
摘要
一种水溶性的共价连接的 C(60)-卟啉化合物-C(60)Por 被报道显示出增强的 DNA 切割活性。高增强的 DNA 切割活性预计归因于 C(60)Por 对 DNA 的高水溶性和亲和力，以及在辐射下形成的荷分离态 C(60)˙(-)-Por˙(+)的可及性。
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