黑腹果蝇一个包含乙醇脱氢酶结构基因的常染色体小区域的遗传学。VII. 蜗牛基因座和仙人掌基因座周围区域的特征描述。
The genetics of a small autosomal region of Drosophila melanogaster containing the structural gene for alcohol dehydrogenase. VII. Characterization of the region around the snail and cactus loci.
作者信息
Ashburner M, Thompson P, Roote J, Lasko P F, Grau Y, el Messal M, Roth S, Simpson P
机构信息
Department of Genetics, University of Cambridge, England.
出版信息
Genetics. 1990 Nov;126(3):679-94. doi: 10.1093/genetics/126.3.679.
Abstract
The genetic interval 35C to 36A on chromosome arm 2L of Drosophila melanogaster has been saturated for mutations with visible or lethal phenotypes. 38 loci have been characterized, including several maternal-effect lethals (vasa, Bic-C, chiffon, cactus and cornichon) and several early embryonic lethals, including snail and fizzy. About 130 deletions have been used to order these loci. Complex interactions between mutant alleles have been uncovered in the immediate genetic environs of the snail gene, as has further evidence for an interaction between this region and that including the nearby genes no-ocelli and elbow.
摘要
黑腹果蝇2号染色体左臂上从35C到36A的遗传区间已被具有可见或致死表型的突变所饱和。已鉴定出38个基因座，包括几个母性效应致死基因（瓦萨基因、双胸复合体基因、雪纺基因、仙人掌基因和黄瓜基因）以及几个早期胚胎致死基因，如蜗牛基因和模糊基因。大约130个缺失已被用于对这些基因座进行排序。在蜗牛基因的直接遗传环境中发现了突变等位基因之间的复杂相互作用，同时也有进一步证据表明该区域与包括附近的无眼基因和肘部基因的区域之间存在相互作用。
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本文引用的文献
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Mutations and Chromosomal Rearrangements Affecting the Expression of Snail, a Gene Involved in Embryonic Patterning in DROSOPHILA MELANOGASTER.影响果蝇胚胎模式形成的基因 Snail 表达的突变和染色体重排。
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7
The genetics of a small chromosome region of Drosophila melanogaster containing the structural gene for alcohol dehydrogenase. IV: scutoid, an antimorphic mutation.黑腹果蝇一个包含乙醇脱氢酶结构基因的小染色体区域的遗传学。IV：盾形，一种反效等位基因突变。
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8
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Techniques for manipulating chromosomal rearrangements and their application to Drosophila melanogaster. I. Pericentric inversions.染色体重排操作技术及其在黑腹果蝇中的应用。I. 臂间倒位。
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