Intermountain Orthopaedic Specialty Group, LDS Hospital, Salt Lake City, Utah, USA. *Intermountain Orthopaedic Specialty Group, LDS Hospital, Salt Lake City, Utah, USA.
J Arthroplasty. 2011 Dec;26(8):1176-81. doi: 10.1016/j.arth.2010.11.004. Epub 2011 Jan 13.
The purpose of this study was to compare serum metal ion concentrations (chromium and cobalt) in 3 groups, 2 with metal-on-metal articulations and a control metal-on-polyethylene group. Forty-six patients with good to well-functioning hips were recruited for the study. Serum ion levels of all patients were drawn, and Harris Hip Score, University of California, Los Angeles activity score, and radiographs were performed. Serum chromium concentrations were significantly lower in the large head group compared with the small head group (P = .013). There was no difference in the cobalt concentrations between the 2 groups (P = .087). There was a significant difference between both metal-on-metal groups when compared with controls for both chromium and cobalt levels (P = .0005 and P = .0004, control vs small; P = .001 and P = .0001, control vs large, respectively).
本研究的目的是比较三组血清金属离子浓度（铬和钴），两组为金属对金属关节，一组为对照组金属对聚乙烯关节。招募了 46 名功能良好的髋关节患者进行研究。抽取所有患者的血清离子水平，并进行 Harris 髋关节评分、加利福尼亚大学洛杉矶活动评分和 X 线片检查。大头组的血清铬浓度明显低于小头组（P =.013）。两组钴浓度无差异（P =.087）。与对照组相比，两组金属对金属组的铬和钴水平均有显著差异（P =.0005 和 P =.0004，对照组与小头组相比；P =.001 和 P =.0001，对照组与大头组相比）。
