Department of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Brody School of Medicine, Greenville, North Carolina 27834, USA.
J Cardiopulm Rehabil Prev. 2011 May-Jun;31(3):188-92. doi: 10.1097/HCR.0b013e318203339b.
: The primary objective of this study was to determine the prevalence of undiagnosed or untreated obstructive sleep apnea (OSA) in patients undergoing cardiac rehabilitation.
: A total of 132 consecutive patients were screened by Berlin Questionnaire to determine the presence or absence of OSA.
: Fourteen patients did not consent to participate. Of the remaining 118 patients, 20 (17%) were found to have a preexisting formal diagnosis of OSA. Of the remaining 98 patients (69 males and 29 females), 43 (44%) were found to have a high probability of OSA as predicted by the Berlin Questionnaire. There was no significant difference in the prevalence (P < .05) between males (29/69, 42%) and females (14/29, 48%) who were predicted to have OSA. Similarly, no significant differences were observed in the ages or body mass index between OSA and non-OSA patients. A significantly greater frequency (P < .05) of coronary artery disease was observed in the OSA group than in the non-OSA group.
: Overall, the rate of preexisting and predicted OSA (53%) suggests a high prevalence of OSA in patients with cardiovascular diseases in a cardiac rehabilitation setting. Moreover, the high rate of undiagnosed OSA, as suggested by the Berlin Questionnaire, further adds to the growing literature that a large number of patients with significant cardiovascular disease carry the burden of sleep disordered breathing.
本研究的主要目的是确定在接受心脏康复的患者中未诊断或未经治疗的阻塞性睡眠呼吸暂停(OSA)的患病率。
通过柏林问卷对 132 例连续患者进行筛查,以确定是否存在 OSA。
有 14 名患者不同意参与。在其余的 118 名患者中,有 20 名(17%)患者被发现有先前存在的 OSA 正式诊断。在其余 98 名患者(69 名男性和 29 名女性)中,有 43 名(44%)根据柏林问卷预测患有 OSA 的高可能性。预测患有 OSA 的男性(29/69,42%)和女性(14/29,48%)之间的患病率(P <.05)没有显著差异。同样,在 OSA 和非 OSA 患者之间,年龄或体重指数之间也没有观察到显著差异。在 OSA 组中,冠状动脉疾病的发生频率明显高于非 OSA 组(P <.05)。
总的来说,预先存在和预测的 OSA(53%)的发生率表明心血管疾病患者在心脏康复环境中 OSA 的患病率较高。此外,柏林问卷提示的未诊断 OSA 的高发生率进一步增加了越来越多的文献,即大量患有严重心血管疾病的患者存在睡眠呼吸障碍的负担。