Department of Pediatric Gastroenterology and Nutrition, Emma's Children's Hospital/AMC, Amsterdam, the Netherlands.
J Pediatr Gastroenterol Nutr. 2011 Apr;52(4):442-5. doi: 10.1097/MPG.0b013e3181ef8e3c.
The aim of the study was to determine the frequency of functional constipation according to the Rome III criteria in children with morbid obesity and to evaluate by measuring colonic transit times (CTTs) whether decreased colonic motility is present in these children.
Ninety-one children with morbid obesity ages 8 to 18 years, entering a prospective, randomized controlled study evaluating the effect of an outpatient versus inpatient treatment program of obesity, participated. All of the children filled out a standardized questionnaire regarding their bowel habits, and CTTs were measured using radioopaque markers. Food diaries were also recorded to evaluate their diet.
A total of 19 children (21%) had functional constipation according to the Rome III criteria, whereas 1 child had functional nonretentive fecal incontinence. Total CTT exceeded 62 hours in only 10.5% of the children with constipation, and among them, 2 had a total CTT of >100 hours. In the nonconstipated group 8.3% had a delayed CTT. Furthermore, no difference was found between the diet of children with or without constipation, specifically not with respect to fiber and fat intake.
Our study confirms a high frequency of functional constipation in children with obesity, using the Rome III criteria. However, abnormal colonic motility, as measured by CTT, was delayed in only a minority of patients. No relation was found between constipation in these children and fiber or fat intake.
本研究旨在根据罗马 III 标准确定病态肥胖儿童功能性便秘的频率，并通过测量结肠通过时间（CTT）评估这些儿童是否存在结肠蠕动功能下降。
91 名 8 至 18 岁的病态肥胖儿童参与了一项前瞻性、随机对照研究，评估门诊与住院肥胖治疗方案的效果。所有儿童都填写了一份关于他们的排便习惯的标准化问卷，并使用不透射线标志物测量 CTT。还记录了饮食日记以评估他们的饮食。
根据罗马 III 标准，共有 19 名儿童（21%）患有功能性便秘，而 1 名儿童患有功能性非潴留性粪便失禁。仅 10.5%的便秘儿童 CTT 超过 62 小时，其中 2 名 CTT 超过 100 小时。在非便秘组中，8.3%的儿童 CTT 延迟。此外，便秘儿童和非便秘儿童的饮食没有差异，特别是在纤维和脂肪摄入方面没有差异。
我们的研究使用罗马 III 标准证实了肥胖儿童功能性便秘的高频率。然而，只有少数患者出现异常结肠蠕动功能，如 CTT 所测量的。在这些儿童中，便秘与纤维或脂肪摄入之间没有关系。
