具有组织学特征改变的复发性甲状腺癌。
Recurrent thyroid cancer with changing histologic features.
作者信息
Shiller S Michelle, Konduri Kartik, Harshman Leeanne K, Welch Brian J, O'Brien John C
机构信息
Departments of Pathology (Shiller), Oncology (Konduri), Nuclear Radiology (Harshman), Endocrinology (Welch), and Surgery (O'Brien), Baylor University Medical Center at Dallas and Baylor Sammons Cancer Center, Dallas, Texas.
出版信息
Proc (Bayl Univ Med Cent). 2010 Jul;23(3):304-10. doi: 10.1080/08998280.2010.11928639.
We present the case of a 57-year-old woman diagnosed with breast cancer and a thyroid mass that was suspicious for cancer. The breast cancer was estrogen and progesterone receptor negative, HER2/neu borderline, with a high proliferative index. Treatment of this cancer took precedence. Nine months later, a total thyroidectomy was done for papillary thyroid cancer with metastases to 2 of 8 perithyroid lymph nodes. Postoperative radioactive iodine ablation was given. Recurrent thyroid disease was found in the right neck 1 year later and was resected; no radioactive iodine was given at that time. After 2½ years, the cancer recurred as a more highly aggressive, undifferentiated anaplastic thyroid carcinoma. Treatment is discussed.
我们报告一例57岁女性病例，该患者被诊断患有乳腺癌以及一个疑似癌症的甲状腺肿块。乳腺癌雌激素和孕激素受体阴性，HER2/neu临界状态，增殖指数高。这种癌症的治疗优先进行。九个月后，因甲状腺乳头状癌伴8个甲状腺周围淋巴结中的2个转移而进行了全甲状腺切除术。术后给予放射性碘消融治疗。1年后右侧颈部发现复发性甲状腺疾病并进行了切除；当时未给予放射性碘治疗。2年半后，癌症复发，表现为侵袭性更强的未分化间变性甲状腺癌。对治疗进行了讨论。
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